The Institute of Pharmacology and Toxicology of the Medical Faculty of the Ruhr University Bochum is seeking to fill the position of a part-time (65%) scientific assistant (m-w-d) as soon as possible as part of a research project funded by the German Research Foundation. The position is initially limited to 3 years. Depending on the tasks assigned and the fulfillment of personal requirements, remuneration will be paid up to pay group 13 TV-L.
The Institute of Pharmacology and Toxicology, headed by Professor Ralf Benndorf, is involved in translational research projects in the field of pharmacological cardiovascular and tumor research and is responsible for teaching pharmacology and toxicology to students of human medicine within the Faculty of Medicine.
The candidate will investigate questions of personalized therapy of cardiovascular diseases (arterial hypertension, atherosclerosis, aortic aneurysms) using cell cultures and genetically modified mouse lines. The candidate must be willing to familiarize him/herself with cell/molecular biological, microscopic, biochemical and animal experimental techniques. The possibility of a doctorate is given.
Pharmacist, biologist or biochemist as doctoral candidate in the field of cardiovascular research
Activities and responsibilities
- Implementation of cell biological (including signal transduction analyses in vascular cells), protein biochemical and molecular biological methods with a thematic focus on “personalized therapy of cardiovascular diseases”
- FRET microscopy-based analysis of receptor-receptor interactions
- Stable transduction of vascular cells and cell lines using lentiviral vectors
- Participation in animal experiments on the topic of “arterial hypertension, atherosclerosis and aortic aneurysms”
- Histologic and immunohistologic analyses
- Documentation, evaluation and presentation of results and writing of publications
Qualification profile
- Completed studies in pharmacy, biochemistry, biology, veterinary medicine, biotechnology or a comparable degree program
- Experience in cell biology, protein biochemistry and molecular biology techniques is an advantage.
- Authorization to carry out animal experiments independently (proven by FELASA Category B certificate) is an advantage
- Excellent knowledge of German and very good knowledge of English
- Knowledge of standard histological or microscopic techniques is an advantage
We offer
- A qualified induction training
- Support from and collaboration with competent colleagues
- State-of-the-art equipment and laboratory facilities, a broad range of methods, a highly motivated research environment in a collegial, committed team.
- Scientific questions with a strong link to clinical-medical application
- Opportunity for further training as a DGPT specialist pharmacologist
Prof. Dr. Ralf Benndorf
Director of the
Institute of Pharmacology and Toxicology
Ruhr University Bochum
Building MA/1/40
University Road 150
44801 Bochum
E-Mail: email