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Postdoctoral researcher (f/m/d) in the field of Translational Immunology / Infectious diseases
Uniklinik Köln
Cologne, North Rhine-Westphalia
Remote Work (optional)
Biochemistry
Molecular biology
Immunology
Microbiology
Molecular biology
At the Faculty of Medicine, University of Cologne over 1.800 scientists are engaged in research, ranging from basic sciences to clinical application, as well as teaching and health care. Together with the University Hospital Cologne the faculty maintains 58 clinics, research institutes and centres. The Faculty of Medicine and the University Hospital Cologne are embedded in the scientifically highly active Rhine region. They have strong contacts to and alliances with the surrounding universities and non-university research institutions guaranteeing scientific excellence in research.
The Department I of Internal Medicine, University Hospital of Cologne is seeking applications for a full-time (100%)
Postdoctoral researcher (f/m/d)
in the field of
Translational Immunology / Infectious diseases
to be employed under a fixed-term contract of 2 years (WissZeitVG) with the possibility for extension.
Severe bacterial infections are causing high morbidity and mortality worldwide, a situation aggravated by the lack of novel antibiotics as well as increasing therapy resistance. Our research groups of Prof. Dr. Dr. Jan Rybniker and Dr. Alexander Simonis focus on the development of new innovative immunotherapies to improve treatment of clinically relevant pathogens such as Pseudomonas aeruginosa. We have recently developed an innovative and highly potent treatment option to combat PA infections based on fully human monoclonal antibodies (mAbs), as presented in our highly acclaimed publication (Simonis et al., Cell 2023). The successful applicant will be tasked with the further development of these promising results and the development of additional mAbs with novel modes of action. The laboratory is strongly supported by the German Center for Infection Research (DZIF) as well as a growing network of local, national and international collaboration partners.
The project will be conducted within the Translational Research Unit - Infectious Diseases (TRU-ID) offering state-of-the-art research facilities at the Center for Molecular Medicine Cologne (CMMC) and the Translational Research in Infectious Disease and Oncology (TRIO) research building. These facilities contain well-equipped laboratories covering biosafety levels (BSL) 1 to 3.
The Department I of Internal Medicine, University Hospital of Cologne is seeking applications for a full-time (100%)
Postdoctoral researcher (f/m/d)
in the field of
Translational Immunology / Infectious diseases
to be employed under a fixed-term contract of 2 years (WissZeitVG) with the possibility for extension.
Severe bacterial infections are causing high morbidity and mortality worldwide, a situation aggravated by the lack of novel antibiotics as well as increasing therapy resistance. Our research groups of Prof. Dr. Dr. Jan Rybniker and Dr. Alexander Simonis focus on the development of new innovative immunotherapies to improve treatment of clinically relevant pathogens such as Pseudomonas aeruginosa. We have recently developed an innovative and highly potent treatment option to combat PA infections based on fully human monoclonal antibodies (mAbs), as presented in our highly acclaimed publication (Simonis et al., Cell 2023). The successful applicant will be tasked with the further development of these promising results and the development of additional mAbs with novel modes of action. The laboratory is strongly supported by the German Center for Infection Research (DZIF) as well as a growing network of local, national and international collaboration partners.
The project will be conducted within the Translational Research Unit - Infectious Diseases (TRU-ID) offering state-of-the-art research facilities at the Center for Molecular Medicine Cologne (CMMC) and the Translational Research in Infectious Disease and Oncology (TRIO) research building. These facilities contain well-equipped laboratories covering biosafety levels (BSL) 1 to 3.
Postdoctoral researcher (f/m/d) in the field of Translational Immunology / Infectious diseases
Activities and responsibilities
Your tasks:
- Development/ production and modification of monoclonal antibodies from patient-derived B cells
- In vitro and in vivo validation of monoclonal antibodies
- Development of therapeutic strategies and contribution to the clinical trial planning
- Supervision and training of junior members and technicians in the lab
- Close cooperation with our medical, industrial and academic collaboration partners
- Presentation of the data within meetings as well as national and international congresses
- Publication of the results in high-impact journals
Qualification profile
Your profile:
- You hold a PhD in molecular biology, immunology, or equivalent
- Strong background in molecular biology/immunology, microbiology and/or biochemistry
- Experience in state-of-the-art advanced multi-color flow cytometry
- Experience with mouse models, experimental procedures, and animal handling is preferred
- Previous work with BSL2 bacterial organisms is desirable but no prerequisite
- A high level of motivation and the ability to work effectively in a team
- Excellent English communication skills, both spoken and written
- Strong analytical and problem-solving skills
- Excellent data reporting and communication skills
We offer
We offer:
Applications from female candidates are expressly welcome and will be given priority in the event of equal suitability, competence and professional performance.
People with disabilities are welcome to apply and will be treated preferentially in the event of equal suitability and qualification.
- Participation in an innovative translational project with a clear prospect of improving the chances of cure for patients affected by multidrug-resistant pathogens
- A creative and innovative research environment with full access to state-of-the-art technology platforms to carry out cutting edge research
- Multiple opportunities to design, implement and lead your own research projects
- Strong support for personal career development
- A constantly growing team of highly motivated researchers and technical staff
- Training in a wide range of techniques in the field of molecular and cellular biology, infectious diseases, and immunology
- Flexible working time models to support family life
Applications from female candidates are expressly welcome and will be given priority in the event of equal suitability, competence and professional performance.
People with disabilities are welcome to apply and will be treated preferentially in the event of equal suitability and qualification.
Please address enquiries (but not your application!) to Dr. Tony Müller (email).
Have we awakened your interest? Please submit your application (including a cover letter, detailed CV, list of publications, two references and a brief statement of research interests) via email to
Claudia Wirges
Department of Infectious Diseases
Team Assistance
email
Full-Time
, Temporary
Postdoc
Updated at
09/20/2024
While applying for the job please refer to jobvector
and use the following reference number:
PD-ID-24
Workplace
Job location
Kerpener Str. 62
50937 Cologne
North Rhine-Westphalia
Germany
Remote Work (optional)
Good to reach from...
- Düsseldorf
- Wuppertal
- Bonn
- Mönchengladbach
- Aachen
- Oberhausen
Salary
The value indicated here represents the average annual gross salary for comparable positions.
€ 55,028
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