Header image Glycothera Development GmbH

GlycoThera Pharmaceutical Services is a leading global service provider for contract development and analytics for biotherapeutics at all stages of product life cycle. With our expertise in the development of biologics (recombinant proteins such as monoclonal antibodies, cytokines and hormones), manufacturing sciences, analytics, quality control and regulatory strategy we support a broad range of clients globally, from emerging biotech startups to leading global pharmaceutical companies.

For our site in Julich (Germany) we are looking for a highly motivated scientist to join our Upstream Process Development team. The main area of responsibility will be the development of upstream processes intended for the manufacture of recombinant proteins under GMP.

Scientist (m/f/d) Upstream Process Development

(full-time, permanent)

The Julich site focusses on small-scale process development for the manufacture of recombinant proteins up to readiness for transfer into pilot scale. Our well-equipped laboratories as well as established high-class analytical infrastructure support targeted, high-throughput development. At the same time, we are striving for innovative and efficient approaches to process development and welcome fresh thinking combined with solid skills. You will be part of a team that values respect, trust, reliability and positivity

Main area of responsibility:

Independent planning, execution and documentation of small-scale mammalian cell culture processes (15 mL to 10 L)
Adequate documentation of all work
Application of quality by design principles to achieve project goals like specific product quality profiles or enhanced process yields
Evaluation of cell culture process as well as product quality results against agreed targets to plan subsequent project steps
Presentation of main results and project status in internal meetings
Support of Tech Transfer of small-scale processes to the customer (technical documentation and potentially on-site support)
Maintenance of databases and data mining
Training and supervision of lab technicians
Support the team with occasional weekend duties

Required experience:

Master in Biotechnology, Biology or other relevant education with several years of work experience in the area of upstream process development (mammalian cell culture)
End-to-end understanding and hands-on expertise of upstream process from vial thaw to harvest clarification
Sound understanding of major steps involved in the development of a biopharmaceutical (process development, process lock, scale-up, tech transfer and process characterization, process validation)
Hands-on experience with common fermentation systems like ambr™15, ambr™250, Wave bioreactor, 10 L bioreactor (glass vessel, single use), incl. related software
Sound statistical knowledge and experienced in the use of statistical software like JMP and MODDE, SIMCA
Ideally experienced in protein characterization
Familiar with common quality principles (GMP, ISO:9001, ALCOA)

You are a smart, proactive and solution-driven scientist with a hands-on attitude who is able to independently progress projects, prioritize tasks adequately and work against tight timelines. At the same time you maintain a high quality standard in your work, support the team and foster a sense of positivity. The team´s success is your success.

Language: English, German is highly beneficial.
Professional experience: Industrial work experience (biotechnology/biopharma) is highly appreciated.

What we offer:

Our Julich site with currently 40 employees offers an innovative, vibrant and multicultural environment that gives you the chance to bring in all of your competencies, and together with a highly motivated team drive the change and develop personally. We believe in a culture of respect, trust, reliability and positivity.

Interested? Then please send your full application as a PDF including earliest start date and salary expectations online.

Glycothera Development GmbH Germany GmbH
Karl-Heinz-Beckurts-Str. 13
52428 Jülich

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Full-Time , Permanent

Specialist

Updated at 06/04/2025

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