CatalYm GmbH is a clinical-stage biotechnology company dedicated to advancing cancer treatment through pioneering Visugromab, a recombinant antibody targeting the immunosuppressive cytokine GDF-15. Under physiological conditions, GDF-15 is essential in feto-maternal tolerance and protection of injured tissues. In cancer, GDF-15 is markedly overexpressed across various tumor types, hindering the body's ability to mount effective immune defenses against tumors and contributing to resistance to treatment. Visugromab is designed to neutralize the activity of GDF-15, reinvigorate anti-tumor immune responses, and enhance the activity of cancer immunotherapy. In our commitment to advancing Visugromab, we're looking for a dedicated Associate Scientist to join our research team and contribute to making a difference for cancer patients.

Research Associate (m/f/d) - Immuno-Oncology

The selected candidate will be a member of the Discovery Biology team and will contribute to the advancement of our understanding of visugromab’s mechanism of action and the identification of novel drug combinations for cancer therapy.

Your tasks and responsibilities:

Design, execution and analysis of in vitro experiments to understand the impact of GDF-15/ GDF-15 blockade on cancer/ immune cell interactions
Establish and optimize in vitro assays using cell-free and cell-based assays
Work with minimal supervision independently and manage multiple projects simultaneously
Independently analyze data sets, maintenance of electronic notebook records and present data in research updates to project teams and R&D management
Coordinate and oversee the shipment process for test reagents for collaborators
Actively participate in day-to-day organization of laboratory management

Your profile:

BTA/CTA/MTA with minimum 3 years of professional experience or B.Sc. with minimum 1 year of professional experience or M.Sc. or comparable degree in biology, immunology, biomedicine, biotechnology or related disciplines
Strong hands-on experience in cellular and molecular biological techniques such as cell culture, immune cell isolation from human PBMCs, multicolor flow cytometry, ELISA, Western blot, qRT-PCR, and cytotoxicity assays
Training in tissue culture, transfection, reporter assays, RNA/DNA/protein preparation and analysis)
Familiarity with the software applications GraphPad Prism, FlowJo, and MS Office applications is desirable, knowledge in the field of statistical analysis is a plus
Knowledge of tumor immunology, immunology, cancer, immunotherapies is a plus
A good command of written and spoken English, proficiency in German is a plus
Strong aptitude for working in a team, good communication and organizational skills
Excellent problem-solving abilities, attention to detail and adaptability
A work permit for Germany is mandatory

We offer:

The opportunity to contribute to research directly impacting cancer therapy and clinical trials
Comprehensive training to enhance your scientific, technical, and interpersonal skills
A role in a pioneering environment as part of a dynamic biotech company on the rise
A collegial atmosphere characterized by a driven and supportive team
Opportunity for flexible work schedules and remote work arrangements, within the framework of company policies and dependent on project requirements
A secure and permanent employment contract

The position is located at the Innovations- und Gründerzentrum Biotechnologie (IZB) in Martinsried.

Applications for this position should be uploaded via the online system and include a cover letter indicating Job ID CAT-AS, your CV, and references as well as salary expectations.

We use the “Recruiter on Demand” service by Constares. A Constares Consultant is managing this position. For further questions, please reach out to Simon Augustyn.

Apply now

Full-Time , Permanent

Specialist

Updated at 09/13/2024

While applying for the job please refer to jobvector and use the following reference number: CAT-AS

Research Associate (m/f/d) – Immuno-Oncology

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