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PhD student position in Immunology at the University of Lübeck, Germany

Our Laboratory in the Institute for Systemic Inflammation Research ( www.isef.uni-luebeck.de ; from January 2017 in the new Institute for Nutrition Medicine) at the University of Lübeck works on the development and function of antibodies. IgG antibodies are not only effector molecules of pathogenic and pro-inflammatory immune responses but can also be mediators of tolerogenic immune responses such as regulatory T cells. The inhibitory function is mediated through a specific kind of IgG Fc glycosylation. Our laboratory has discovered that antigen-specific sialylated IgG antibodies can be used to inhibit pro-inflammatory immune responses in an antigen-specific manner. Now, we investigate how differentially glycosylated pro-inflammatory or immunosuppressive IgG antibodies develop and function in human and mice. Therefore, we also produce our own monoclonal antibodies with different glyco-forms to investigate their potential in different autoimmune, allergy, vaccination and transplantation models.
For upcoming research projects we are looking for a highly motivated PhD student candidate. The PhD student will be part of the Research Training Group GRK1727 ( https://www.grk1727.uni-luebeck.de/grk1727/ ).
Please contact Prof. Marc Ehlers (email: marc.ehlers@uk-sh.de) for further informations and application (via email).

Contact detail

How to apply:
via email: marc.ehlers@uk-sh.de
Send application to
Prof. Marc Ehlers
University of Lübeck
Ratzeburger Allee
23562 Lübeck
email: marc.ehlers@uk-sh.de

Job profile

Working hours
Contract duration
Type of job
PhD Project
Work experience
job experience is not required
Germany (Schleswig-Holstein)
Working place
23562 Lübeck
Area of expertise
Biology & Life Sciences, Human medicine