PhD student position in Immunology in the Research Training Group GRK1727 at the University of Lübeck, Germany

Our Laboratory in the Institute for Systemic Inflammation Research ( ); from January 2017 in the new Institute for Nutrition Medicine ( ) at the University of Lübeck works on the development and function of antibodies. IgG antibodies are not only effector molecules of pathogenic and pro-inflammatory immune responses but can also be mediators of tolerogenic immune responses such as regulatory T cells. The inhibitory function is mediated through a specific kind of IgG Fc glycosylation. Our laboratory has discovered that antigen-specific sialylated IgG antibodies can be used to inhibit pro-inflammatory immune responses in an antigen-specific manner (Oefner et al, JACI 2012, 129(6):1647-1655; Karsten et al, Nature Medicine 2012, 18(9):1401-1406; Hess et al, JCI 2013, 123(9):3788–3796; Strait et al, Nature 2015, 517(7535):501-504). Now, we investigate how differentially glycosylated pro-inflammatory or immunosuppressive IgG antibodies develop and function in human and mice. To investigate these projects, we also produce our own monoclonal antibodies with different glyco-forms to investigate their potential in different autoimmune, allergy, vaccination and transplantation models.
For upcoming research projects we are looking for a highly motivated PhD student candidate. The PhD student will be part of the Research Training Group GRK1727 ( ).
Please contact Prof. Marc Ehlers (email: for further informations and application (via email). Deadline: extended 31.01.2017

Contact detail

How to apply:
via email:
Send application to
Prof. Marc Ehlers
University of Lübeck
Ratzeburger Allee
23562 Lübeck

Job profile

Working hours
Contract duration
Type of job
PhD Project
Work experience
job experience is not required
Germany (Schleswig-Holstein)
Working place
23562 Lübeck
Area of expertise
Biology & Life Sciences, Human medicine

About Universität zu Lübeck; Deutschland;

Im ISEF ( werden verschiedene Fragestellungen zur Bedeutung des Immunsystems für die Entwicklung von akut- sowie chronisch-entzündlichen Erkrankungen wie Autoimmunkrankheiten und Allergien bearbeitet.

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