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1 PhD position

Workscope: Research Associate

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Open PositionReference: 09/2015
 
The Center for Molecular Biomedicine / Department of Biophysics at the Friedrich Schiller University Jena is seeking a highly qualified and motivated candidate for

1 PhD position (50%)
in the DFG-funded project “Local UV/VIS light generation for biomedial applications by NIR irradiation of targeted nanoparticles“
Start: July 1st, 2015

Background and aim:
Molecular signaling in cells requires a multitude of complex biochemical machineries relying on spatial and temporal separation as to allow the parallel processing of intracellular “signals”. Studying such locally confined molecular signaling events thus affords their specific manipulation and detection. The proposed experimental study is conceived to achieve this goal by triggering photobiological reactions in the vicinity of identified ion channel proteins in the plasma membrane of living cells with high temporal resolution and narrow local confinement by use of nanometer scale UV/VIS light sources (nanoparticles). The biological response will be monitored in a quantitative manner by the electrophysiological assessment of ion channel function. The overall biological/biochemical aim of this study is to learn how select membrane proteins are regulated by their local environment. The project will be performed in collaboration with the Leibniz Institute of Photonic Technologies, Jena.
 
Methods involved:
 
  • Electrophysiology of ion channels
  • Molecular biological methods of recombinant DNA technology
  • Nanoparticle handling and targeting
  • Fluorescence microscopy and imaging
  • Data analysis and presentation
 
Requirements:
 
  • Master or diploma degree in biochemistry, physiology, biophysics, neurobiology or physics
  • Background in molecular biological and electrophysiological methods and imaging techniques is advantageous
  • Interest in scientific work
  • Self-reliant way of working, team player
  • English skills
 
The position is initially limited to 2 years and can be extended for 1 year. Remuneration is based on terms of the collective agreement for employees of public service (“Tarifvertrag für den öffentlichen Dienst der Länder (TV-L)”). Depending on personal qualifications, the applicant can receive a maximum salary according to payment group E13 TV-L.
 
Disabled persons with comparable qualifications receive preferential status.
 
  
To apply, please send your CV, motivation letter and copies of certificates until March 6th, 2015 to:

Prof. Dr. Stefan H. Heinemann
CMB – Zentrum für Molekulare Biomedizin
Lehrstuhl für Biophysik
Friedrich-Schiller-Universität Jena
Hans-Knöll-Str. 2
07745 Jena  

Or to: stefan.h.heinemann@uni-jena.de
 
If return of documents is desired, please send a sufficiently stamped envelope along. For informal inquiries contact Prof. Dr. Stefan H. Heinemann (phone: 0 36 41 – 9 39 56 50; email: stefan.h.heinemann@uni-jena.de).
 

Contact detail


How to apply:
Prof. Dr. Stefan H. Heinemann
CMB – Zentrum für Molekulare Biomedizin

Lehrstuhl für Biophysik
Friedrich-Schiller-Universität Jena
Hans-Knöll-Str. 2
07745 Jena

Or to: stefan.h.heinemann@uni-jena.de
Send application to
Prof. Dr. Stefan H. Heinemann
CMB – Zentrum für Molekulare Biomedizin

Lehrstuhl für Biophysik
Friedrich-Schiller-Universität Jena
Hans-Knöll-Str. 2
07745 Jena

Or to: stefan.h.heinemann@uni-jena.de

Job profile


Working hours
Part-Time
Contract duration
Temporary
Type of job
PhD Project
Work experience
job experience is not required
Region
Germany (Thüringen)
Working place
07743 Jena
Area of expertise
Biology & Life Sciences, Physics
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