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Doctoral Researcher Position / Genome mining and synthetic biology for antibiotic discovery in anaerobic bacteria

The Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute – in cooperation with the Friedrich Schiller University and the Max Planck Institute for Chemical Ecology are offering an international graduate training program. The
International Leibniz Research School (ILRS Jena)

gives doctoral researchers the possibility to prepare for their PhD exam in an ambitious program providing excellent research conditions. We invite applications for a

Doctoral Researcher Position (Ref.No. ILRS_04/2015)
Genome mining and synthetic biology for antibiotic discovery in anaerobic bacteria

Natural products from microorganisms are a highly prolific source for novel therapeutics, in particular for antiinfectives and antiproliferative agents. In recent years, advances in genome sequencing and developments of molecular tools have provided deeper insights into the genetic codes for these fine-tuned, multifaceted biocatalysts. Furthermore, it has become obvious that the biosynthetic potential of anaerobic microorganisms is highly underestimated.  

The aim of this project to decode and engineer biosynthetic processing lines in these neglected bacteria. Potential applications are the reprogramming the biosynthetic code in the sense of combinatorial biosynthesis and synthetic biology and activation of silent pathways.

Experience in the handling and genetic manipulation of anaerobic bacteria will be a plus.

We expect:
  • a Master’s degree (or equivalent ) in Natural or Life Sciences. Research at ILRS is centred around “Microbial and Biomolecular Interactions”. Candidates about to earn their degree are welcome to apply.
  • high motivation and interest to join one of the research areas of ILRS
  • creativity and interest in shaping your own thesis project
  • an integrative and cooperative personality with enthusiasm for actively participating in our lively community
  • very good communication skills in English
We offer:
  • a top-level research environment
  • efficient supervision by a team of advisors
  • a comprehensive mentoring program (cf. Program of Study)
  • courses in state-of-the-art technologies and soft skills
  • strong communication and interaction between the involved institutions
  • Jena – City of Science: innovative business activities, successful scientific centres and a vibrant cultural scene around the famous Friedrich Schiller University
The three-year Doctoral Researcher position is available starting from June 2015. Salary will be paid according to TV-L (salary agreement for public service employees). HKI is an equal opportunity employer.

Further information:
Prof. Dr. Christian Hertweck, PI, christian.hertweck@hki-jena.de
Dr. Christine Vogler, ILRS Coordinator, ilrs@hki-jena.de

The application process is handled exclusively online. Please acquaint yourself with the scientific projects offered on our website and thoroughly follow the instructions for the online application process:

www.ilrs.hki-jena.de/jobs
 
Deadline for application: March 13, 2015.
Successful applicants will be invited to attend a recruitment meeting in Jena (envisaged date: May 11-13, 2015).
 

Contact detail


How to apply:
The application process is handled exclusively online. Please acquaint yourself with the scientific projects offered on our website and thoroughly follow the instructions for the online application process:
www.ilrs.hki-jena.de/jobs
Send application to
Dr. Christine Vogler, ILRS Coordinator, ilrs@hki-jena.de

 

Job profile


Working hours
Full-Time
Contract duration
Temporary
Type of job
PhD Project
Work experience
job experience is not required
Region
Germany (Thüringen)
Working place
07745 Jena
Area of expertise
Biology & Life Sciences, Chemistry, Pharmaceutics