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Doctoral Researcher Position / Molecular dissection of early signaling response in the green alga Chlamydomonas reinhardtii under the influence of biotic and abiotic factors

The Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute – in cooperation with the Friedrich Schiller University and the Max Planck Institute for Chemical Ecology are offering an international graduate training program. The
International Leibniz Research School (ILRS Jena)

gives doctoral researchers the possibility to prepare for their PhD exam in an ambitious program providing excellent research conditions.
We invite applications for a
 
Doctoral Researcher Position (Ref.No. ILRS_05/2015)
Molecular dissection of early signaling response in the green alga Chlamydomonas reinhardtii under the influence of biotic and abiotic factors

The green unicellular alga Chlamydomonas reinhardtii lives in soil and freshwater and has served as a model organism for a variety of biological processes for decades [1]. Its genome has been sequenced and there is a broad method toolkit available for this microalga. Here, we want to elucidate and compare early signal transduction steps that are triggered after C. reinhardtii is exposed to biotic factors such as the interaction with other microorganisms and abiotic factors such as light.

Former studies show that Ca2+ signaling relays information from the eyespot of the alga, which represents a primitive visual system, to the flagella, and calcium binding proteins have been identified in the flagella and eyespot subproteomes [2, 3]. Also kinases and phosphatases are present in these organelles and reversible phosphorylation can play an important role there [4, 5]. While several photoreceptors of C. reinhardtii are known that perceive light of different wavelengths [6, 7], knowledge about how these signaling components and mechanisms act to mediate early contact response in C. reinhardtii in the presence of other microrganisms remains elusive.
Here, we want to analyze early signaling steps based on reporter gene lines after triggering biotic and abiotic signaling cascades. 

[1] Merchant et al. 2007, Science 318, 245-251.
[2] Pazour et al. 2005, J Cell Biol 170, 103-113.
[3] Schmidt et al. 2006, Plant Cell 18, 1908-1930.
[4] Wagner et al. 2008, Plant Physiol 146, 772-288.
[5] Boesger et al. 2014, Methods Mol Biol 1158, 187-202.
[6] Hegemann 2008, Annu Rev Plant Biol 59, 167-189.
[7] Beel et al. 2012, Plant Cell 24, 2992-3008.

We expect:
  • a Master’s degree (or equivalent ) in Natural or Life Sciences. Research at ILRS is centred around “Microbial and Biomolecular Interactions”. Candidates about to earn their degree are welcome to apply.
  • high motivation and interest to join one of the research areas of ILRS
  • creativity and interest in shaping your own thesis project
  • an integrative and cooperative personality with enthusiasm for actively participating in our lively community
  • very good communication skills in English

We offer:
  • a top-level research environment
  • efficient supervision by a team of advisors
  • a comprehensive mentoring program (cf. Program of Study)
  • courses in state-of-the-art technologies and soft skills
  • strong communication and interaction between the involved institutions
  • Jena – City of Science: innovative business activities, successful scientific centres and a vibrant cultural scene around the famous Friedrich Schiller University
The three-year Doctoral Researcher position is available starting from June 2015. Salary will be paid according to TV-L (salary agreement for public service employees). HKI is an equal opportunity employer.

Further information:
Prof. Dr. Maria Mittag, PI, maria.mittag@uni-jena.de
Dr. Christine Vogler, ILRS Coordinator, ilrs@hki-jena.de

The application process is handled exclusively online. Please acquaint yourself with the scientific projects offered on our website and thoroughly follow the instructions for the online application process:
www.ilrs.hki-jena.de/jobs

Deadline for application: March 13, 2015.
Successful applicants will be invited to attend a recruitment meeting in Jena (envisaged date: May 11-13, 2015).

Contact detail


How to apply:

The application process is handled exclusively online. Please acquaint yourself with the scientific projects offered on our website and thoroughly follow the instructions for the online application process:
www.ilrs.hki-jena.de/jobs
Send application to
Dr. Christine Vogler, ILRS Coordinator, ilrs@hki-jena.de

 

Job profile


Working hours
Full-Time
Contract duration
Temporary
Type of job
PhD Project
Work experience
job experience is not required
Region
Germany (Thüringen)
Working place
07745 Jena
Area of expertise
Biology & Life Sciences