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Ph.D. position

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A DFG-funded Ph.D. position at the Institute of Pathology is open to investigate c-Myc-driven signaling pathways in colorectal cancer. Specifically, a positive feedback loop connecting the oncogene c-Myc and the deacetylase SIRT1 will be studied using mouse models and in vitro assays to evaluate its role for the mechanisms of carcinogenesis and colorectal cancer progression. In the project components of the feedback loop will be investigated with particularly interested in their role in immortalization, tumor metabolism, metastasis and their function in the tumor/ stroma interaction. The Research Group „Signaling in Colorectal Cancer“, which is headed by PD Dr. rer. nat. Antje Menssen is part of the “Deutsches Konsortium für Translationale Krebsforschung” (DKTK) and affiliated to the laboratories of the Experimental Pathology in the Institute of Pathology of the Ludwig-Maximilians-University of Munich. The project is embedded within the DKTK programs oncogenic pathways, stem cells in oncology and molecular diagnostics and offers also collaborative research activities with other members of the DKTK. For more information see:
Menssen, A. PNAS USA 2012 January 24; 109 (4): E187 -96
The position is available immediately. We look forward to your application, which should include a current resume, references and contact details of three referees. Please send your application until 15/09/2014 to:

Contact detail

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PD Dr. rer. nat. Antje Menssen
DKTK AG "Signaling in colorectal cancer" des DKFZ, Heidelberg
Pathologisches Institut der Ludwig-Maximilians-Universität München
Thalkirchnerstr. 36
80337 München

Job profile

Working hours
Contract duration
Type of job
PhD Project
Work experience
job experience is not required
Germany (Bayern)
Working place
80337 München
Area of expertise
Biology & Life Sciences, Human medicine