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Ph.D. student position

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Ph.D. student position

is immediately available at the Chair for Nutrition and Immunology headed by Prof. Dr. Dirk Haller at the Technische Universität München (TUM).

The intestinal tract acts as an important barrier and communication organ at the interface between the luminal environment, including nutritional and microbial factors, and the host. Signals derived from this interplay are transmitted through epithelial, immune, neuronal and hormonal networks and affect intestinal functions as well as peripheral tissues of the host. Inflammatory processes play a particular role in shaping these interactions towards a disease susceptible milieu that favors the development of chronic disorders including inflammatory bowel diseases (IBD) and colorectal cancer.

Unfolded protein responses (UPR) adapt the protein folding capacity of cellular organelles (endoplasmic reticulum (ER) and mitochondria) to the fluctuating physiological demand. UPR mechanisms are essential to sustain epithelial barrier function, production of antimicrobial peptides and proliferative control, three key players in the pathogenesis of inflammatory bowel diseases (IBD) and colorectal cancer. Unlike ER UPR, the role of mitochondrial UPR and altered mitochondrial function in intestinal epithelial cell (IEC) homeostasis is poorly understood. The prime emphasis of this project is on mitochondrial UPR in the context of metabolism and inflammation in the intestine.

We are looking for a highly motivated and enthusiastic PhD student with a Diploma/MSc in Nutrition or Life Sciences. Candidates should have a solid background in either immunology, microbiology, molecular biology and should be willing to work with mouse models.
We offer an exciting research project, well-equipped laboratories and a fruitful scientific atmosphere. The position is available immediately and funded for 3 years. Salary will be determined according to the German collective wage agreement in public service (TV-L 13/ 50%).

TUM is an equal opportunity employer. Therefore women are especially encouraged to apply. Handicapped persons having an equivalent experience will be preferred.

Contact detail

How to apply:
Please send your application until 15.09.2014 to:

Dr. Ingrid Schmöller
Lehrstuhl für Ernährung und Immunologie
85354 Freising-Weihenstephan

or E-Mail: ingrid.schmoeller@tum.de
Send application to
Dr. Ingrid Schmöller
Lehrstuhl für Ernährung und Immunologie
Gregor-Mendel-Str. 2
85354 Freising-Weihenstephan

or E-Mail: ingrid.schmoeller@tum.de

Job profile

Working hours
Contract duration
Type of job
PhD Project
Work experience
job experience is not required
Germany (Bayern)
Working place
85354 Freising - Weihenstephan
Area of expertise
Biology & Life Sciences