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PHD Position available

 Medizinische Hochschule Hannover  Hannover
The Hannover Medical School, the Clinic of Gastroenterology, Hepatology and Endocrinology, is currently offering a position for a PhD Student for a research project funded by the German Research Foundation.
Genetically engineered mouse models (GEMMs) are powerful tools for the functional annotation of the cancer genome. However, in order to introduce genetic alterations into these models, multi-allelic mice need to be generated by traditional breeding, a process that is both time-consuming and expensive.
We have established a novel and highly flexible mouse model of pancreatic cancer that overcomes this limitation and facilitates a more rapid evaluation of defined genetic alterations in pancreatic cancer development using regulatable RNAinterference- technology (Saborowski et al., Genes Dev 2014) in life mice.
We plan to use this technology to identify and functionally characterize putative cancer genes for their role in pancreatic cancer development, microenvironment and maintenance.
The successful candidate is expected to hold a Master’s degree/diploma in molecular biology, biochemistry, biology or related fields, is highly motivated and willing to work in a competitive research field as a member of an international and multidisciplinary team.
The Department of Gastroenterology, Hepatology and Endocrinology (Director: Prof. Dr. med. Michael P. Manns) offers a unique research environment in the field of gastrointestinal diseases, cancer biology, infection biology, tumor immunology, excellent state-of-the-art equipment, a stimulating scientific community and intensive training of scientific and personal skills. Further information about the clinic can be found on our website:
For questions regarding the offered PhD position, please contact Dr. Michael Saborowski under:
Initial contract for 3 years, TV-L (65 %). Equal Opportunities are part of our personnel policy-qualified women are especially invited to apply. Qualified applicants with a disability will be given preference. Please send your application with a cover letter outlining briefly your research experience and own scientific interests within the context of the announced research topic, as well as a complete curriculum vitae including a list of publications and academic references (if available) per e-mail until 15.08.2015.

How to apply:
Please respond via email.
Send application to
Dr. Michael Saborowski
Medizinische Hochschule Hannover
Klinik für Gastroenterologie, Hepatologie and Endokrinologie
Carl-Neuberg-Str. 1
30625 Hannover
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