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PhD student (Doktorand, m/w) in Immunology & Hemostaseology

The Center for Thrombosis and Hemostasis, Department of Hematology, Pneumology and Oncology of the University Medical Center Mainz, laboratory of Dr. Markus Bosmann is seeking a highly qualified:
 
PhD candidate student in Immunology & Hemostaseology (m/f)
 
The University Medical Center Mainz of the Johannes Gutenberg University Mainz is ranked as a leading research institution of Germany having a strong immunology program. Our laboratory is affiliated to the Center for Thrombosis and Hemostasis (CTH), funded by the German Ministry of Education and Research (BMBF) as well as the Department of Hematology, Pneumology and Oncology. Objectives of the PhD program are to create an attractive environment for basic & translational research and improved career opportunities for young researchers.
 
We are looking for a highly motivated PhD candidate student to study the mechanisms of innate and adaptive immunity during sepsis (bacterial infection). The projects aim to investigate the molecular interactions of immune responses and the coagulation system. A special area of interest is the role of macrophage-derived cytokines and related signaling pathways as well as role of novel pathogen associated molecular patterns.

These basic and translational research projects are primarily conducted in surgical mouse models of experimental sepsis (cecal ligation & puncture), and require state-of-the-art techniques in immunology, molecular biology and hemostaseology. Complex mouse breeding strategies and generation of bone-marrow chimeric mice will be performed. In addition, cell culture techniques (isolation of macrophages, neutrophils, platelets) as well as flow cytometry, RT-PCR, ChIP assays, ELISA, Western blotting, bead-based assays, aggregometry, lentiviral transductions, immunostainings, intra-vital microscopy and massive parallel sequencing technologies will be employed.
 
The PhD student will have opportunities in designing as well as conducting independent projects. The duration of the projects will be 3-4 years. Based on individual credentials and experience, an application for extramural PhD stipends is encouraged.
 
An M.Sc. or diploma degree in a relevant field is required and a strong background in Immunology, Molecular Biology and/or Hemostaseology is preferred. Ability in initiating, conducting, evaluating and reporting of research studies is essential. Experiences with tissue cultures, transgenic mouse models and molecular biology methodologies are desirable. Excellent verbal and written communication skills are required.
 
The PhD student will have the opportunity to work with an interdisciplinary and highly motivated team of scientists and clinicians. Further information is available:
 
http://www.cth-mainz.de/cth/professorships-research-groups/juniorgroup-bosmann-exp-research.html?L=1
 

Contact detail


How to apply:
Please send your application materials (CV, letter of motivation, list of references, official transcripts: diplomas, Abiturzeugnis) in English or German to Dr. Markus Bosmann:

 markus.bosmann@unimedizin-mainz.de
 

 Please mention reference number: MB-PhD-2014-7

 
Send application to
Contact Information:
Hr. Dr. Markus Bosmann
Centrum für Thrombose und Hämostase (CTH)
III. Medizinische Klinik für Hämatologie, Onkologie und Pneumologie
Universitätsmedizin Mainz
Langenbeckstr. 1
55131 Mainz
 
Email: markus.bosmann@unimedizin-mainz.de
Tel: 06131-17-8277
 
 

Job profile


Working hours
Full-Time
Contract duration
Temporary
Type of job
PhD Project
Work experience
job experience is not required
Region
Germany (Rheinland-Pfalz)
Working place
55131 Mainz
Area of expertise
Biology & Life Sciences, Agricultural Sciences, Chemistry, Geo Sciences, Computer Sciences, Mathematics, Pharmaceutics, Physics, Human medicine, Healthcare & Public Health, Veterinary Medicine, Biotechnology, Chemical & Process Engineering, Electrical Engineering, Mechanical Engineering, Material Science & Engineering, Medical Engineering
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