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PhD student position in Optogenetics of Synaptic Transmission in Frankfurt, Germany

Workscope: Research Associate

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The Gottschalk lab at the Buchmann Institute for Molecular Life Sciences (Goethe University) offers a PhD student position, beginning May 1st, 2015, for a project on identification and analysis of proteins required for recycling of synaptic vesicles and for synaptic homeostasis. The project is funded through the Collaborative Research Center (SFB) 1080, initially until the end of 2016, to be prolonged along with the new 4-year funding period of the CRC1080.
In the project, all-optical methods are used to screen the genome for genes affecting synaptic vesicle recycling, in the nematode Caenorhabditis elegans . These genes, as well as genes already identified in a pilot screen, will be characterized by genetic, optogenetic, behavioral and physiological methods. Furthermore, rapid freeze fixation following optogenetic neuronal stimulation (“flash-and-freeze”) will be used to assay the structural synaptic phenotypes of these mutants, in a time resolved manner, by electron microscopy, in collaboration with a supervisor.
Prerequisite is an MSc or Diploma either in Neurobiology, Cell Biology, Molecular Biology, or Biochemistry. We seek for a candidate with a strong background in molecular biology, neurobiology, genetics and fluorescence microscopy. Experience with C. elegans is certainly welcome, but not a must. Information on the lab can be found at http://www.biochem.uni-frankfurt.de/index.php?id=8.
Please send your application electronically (a.gottschalk@em.uni-frankfurt.de), including a CV, research statement/motivation letter, description of previous experience, certificates and transcripts, as well as names of three references, no later than March 17th, 2015.

Contact detail

How to apply:
17th March 2015
Send application to
A. Gottschalk
Buchmann Institute for Molecular Life Sciences
Max von Laue Strasse 15
D-60438 Frankfurt

Job profile

Working hours
Can be Full-Time or Part-Time
Contract duration
Type of job
PhD Project
Work experience
job experience is not required
Germany (Hessen)
Working place
D-60438 Frankfurt
Area of expertise
Biology & Life Sciences