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Postdoctoral Fellow in Biochemistry/Biophysics: Mechanism of ATP-dependent Chromatin Remodeling

Join us at the Mueller-Planitz group to study ATP-dependent nucleosome remodeling enzymes. These factors are molecular machines that transform the nucleosomal organization of eukaryotic chromatin. Some remodeling enzymes can deposit or evict nucleosomes; others reposition entire nucleosomes along DNA. Collectively they enable critical switches in the structural state of chromatin that are needed during development or upon environmental changes.

The group:
The Mueller-Planitz group is based in Munich, Germany, and is part of the Molecular Biology Department of the Adolf-Butenandt-Institute and the newly-built BioMedical Center of the Ludwig-Maximilians-Universität. The group is currently funded by three DFG grants and is part of the SFB 1064 initiative “Chromatin dynamics”. State of the art equipment (e.g. high-end fluorimeters and mass spectrometers critical for the project) is available in house.

The position:
The mission is to study the mechanism of several related nucleosome remodeling complexes. By decoding their design, we will appreciate their commonalities and differences, and we will obtain insight into the inner workings of these fascinating molecular machines. You will:
  • Perform cutting edge fluorescence techniques including time-resolved FRET and innovative structural techniques such as protein crosslinking coupled to mass spectrometry.
  • Gain deep understanding of the enzymology of chromatin-modifying complexes.
The position (E13) is for 2 years initially with the possibility to extend.

Who you are:
You are someone with excellent scientific and organizational skills. Because you are fully committed to science, you enjoy going the extra mile to further test and challenge your hypotheses. You have good communication skills, and you are fully proficient in oral and written English. Teamwork comes natural to you. We expect outstanding motivation, creativity, critical and analytical thinking and a strong scientific enthusiasm. You have:
  • A PhD degree in a relevant field, e.g. Biochemistry or Biophysics, and a relevant publication record.
  • Broad-based interest in mechanisms at the molecular level and chromatin biology.
  • Strong background (theoretical and practical) in fluorescence techniques.
  • Extensive practical experience in protein biochemistry, including protein purification by FPLC. Knowledge of insect cell culture is a plus. 
How to apply:
Please send your full application and a list of ideally three references to fmp.applications@med.uni-muenchen.de. Please include your scientific interest, your career goals and your motivation for joining the group in your application.
 
The Ludwig-Maximilians-Universität is an Equal Opportunity Employer.
 

Contact detail


How to apply:
Please send your full application and a list of ideally three references by email to fmp.applications@med.uni-muenchen.de.

Please mention the JobVector ad number and include your scientific interest, your career goals and your motivation for joining the group in your application.

 
Send application to
Dr. Felix Müller-Planitz

Email: fmp.applications@med.uni-muenchen.de
Web: http://www.molekularbiologie.abi.med.uni-muenchen.de/ueber_uns/mueller_planitz/index.html

 

Job profile


Working hours
Full-Time
Contract duration
Temporary
Type of job
Postdoc
Work experience
job experience is not required
Region
Germany (Bayern)
Working place
80336 München
Area of expertise
Biology & Life Sciences, Physics, Biotechnology
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