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Characterisation of Aspergillus fumigatus mutants regarding their interaction with human leucocytes

The Jena School for Microbial Communication (JSMC) is funded by the German Excellence Initiative. JSMC is an ambitious Graduate School with over 150 doctoral researchers who are educated in a structured, interdisciplinary training program based on top-level fundamental research. It conceptionally combines different research areas to a comprehensive picture of microbial communication (www.jsmc.uni-jena.de). Institutes at five faculties of the Friedrich Schiller University Jena, six non-university research institutes as well as 12 partner companies are participating in this cutting-edge research and training program.
The Graduate School of Excellence ‘JSMC’ invites applications for a
Doctoral Researcher Position TV-L E13 65% (Ref. No. 119/2015)
to conduct research on the project
Characterisation of Aspergillus fumigatus mutants regarding their interaction with human leucocytes

At the inferface of basic and clinical research, the PhD student will investigate recognition, initial interaction and phagocytosis of Aspergillus fumigatus conidia by healthy and patient-derived human leucocytes. Use of conidia with mutations in genes encoding for surface molecules and for molecules in the secondary metabolism will promote the understanding of the pathophysiology of invasive aspergillosis which is essential for improvement of prophylaxis and therapy in patients.
More projects details here: www.jsmc.uni-jena.de/phd-program/fellowship-application/vacant-projects/
We expect:
  • a Master’s degree (or equivalent) in Natural Sciences (preferably Biology, Biomedicine). Candidates about to earn their degree are welcome to apply.
  • desirable methodological skills: flow cytometry, immuno-assays (ELISA), cell culture, molecular biology ((q)RT-PCR), basic skills of microbiology
  • high motivation and interest to join one of the interdisciplinary research areas of JSMC
  • creativity and interest to shape your own thesis project
  • an integrative and cooperative personality with enthusiasm for actively participating in the lively JSMC Community
  • very good communication skills in English (instruction language at JSMC)
We offer:
  • a highly communicative atmosphere within a scientific network providing top-level research facilities
  • a doctoral researcher position (TV-L E13, 65%) with guaranteed funding for one and a half years based on the regulations of the German Research Foundation as well as generous research funding with the possibility of funding extension for completion of the PhD project
  • a comprehensive mentoring program with supervision by a team of advisors
  • a top-level PhD training program with courses in state-of-the-art research technologies and soft skills
  • Jena – City of Science: a young and lively town with dynamic business activities, successful scientific centers of innovation and a vibrant cultural scene around the famous Friedrich Schiller University
Friedrich Schiller University Jena is an equal opportunity employer. Disabled persons with comparable qualifications receive preferential status.

Contact detail

How to apply:
The application procedure takes place exclusively online via the JSMC website:

Please acquaint yourself with the open PhD projects and the application process described on this website. Selected applicants will be invited to the JSMC Recruitment Meeting in Jena, Germany, in January 2016. Awarding decisions will be made shortly thereafter, allowing the projects to start immediately.
Application deadline: November 17th, 2015
Send application to
Katja Präfcke
Neugasse 23
07743 Jena

Email: apply@jsmc.info

Job profile

Working hours
Contract duration
Type of job
PhD Project
Work experience
job experience is not required
Germany (Thüringen)
Working place
07743 Jena
Area of expertise
Biology & Life Sciences, Chemistry