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Master thesis: Neurodegenerative diseases of the retina

The Experimental Eye Research Institute at the Ruhr-University Bochum is part of the University Eye Clinic Bochum. The lab focuses experimental basic research in the field of ophthalmology. Mechanical processes, ischemic damage, excitotoxicity, and immunological processes play a decisive part in the pathophysiology of several eye diseases like glaucoma or retinal ischemia. Therefore, current research subjects of our lab are the identification and investigation of cell death mechanisms which contribute to the disease progressions as well as the testing of innovative therapeutic agents.
 
Project:
The project is based on well-established animal models which are used to induce retinal ganglion cells death and axonal degeneration.
Subsequent to these in vivo studies and within the framework of the master thesis the extend of retina and optic nerve damage should be analyzed and the underlying mechanisms (contribution of immune cells, cell death mechanisms..) should be identified.
 
Methods:
Immunohistochemistry, protein biochemistry (Western Blot and ELISA) and molecular biology (qRT-PCR).
 
Requirements:
A great amount of motivation and patience as well as independent working are necessary for a successful completion of the planed experiments.
Previous knowledge of immnohistochemistry and/or protein analyses are welcomed.
 
We offer:  
A fully-equipped, modern lab; careful familiarization as well as an excellent support in all parts of the master thesis
 
Begin/Duration: immediately/as required

Contact detail


How to apply:
via email to: eeri@rub.de
Send application to
If you interest, please send your application (including CV and personal record) via email to:
PD Dr. Stephanie Joachim
Head of the Experimental Eye Research Institute, University Eye Hospital
In der Schornau 23-25, 44892 Bochum
Tel.: 0234-299-3156
E-Mail: eeri@rub.de / Web: http://www.rub.de/eeri

Job profile


Working hours
Full-Time
Contract duration
Temporary
Type of job
Diploma Thesis/Master's Thesis
Work experience
job experience is not required
Region
Germany (Nordrhein-Westfalen)
Working place
44892 Bochum-Langendreer
Area of expertise
Biology & Life Sciences, Human medicine, Veterinary Medicine
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