Microarray-based Development of Fluorescent Probes for High-End Microscopy

The Rudolf Virchow Center / Research Center for Experimental Biomedicine of the
 
University of Würzburg offers a position as

Docotral Researcher (f/m)
 
Microarray-based Development of Fluorescent Probes for High-End Microscopy


We are looking for a highly motivated doctoral researcher to join the group of Hans Maric. By combining the principles of synthetic chemistry, processes of living organisms and modern automatization technologies we characterize protein interactions on the molecular level. Our aim is to use the gained insight to develop peptides, small molecules, proteins and nanobodies for clinical and research applications.

Project: The goal of the project will be to develop protein binding molecules superior to conventional antibodies in terms of size and binding efficiency and hence ideally suited as fluorescence labels for high-end microscopy. State-of-the-art peptide microarrays will be produced and analysed by highly advanced robotic systems and numerous chemical, biochemical and molecular biological methods will be applied. See also Maric H.M. et al. Nature Chem. Biol. 2017, Maric H.M. et al. Angewandte Chem. 2015 and Maric H.M. et al. Nature Commun. 2014

Requirements:
You possess a Master-degree in any of the life sciences, chemistry or engineering and a strong background in Biochemistry. Experiences related to protein and peptide chemistry and protein characterisation methods are beneficial. You have good English skills and you like to work and interact across disciplines. To change the status-quo and help to create new breakthroughs you prefer to perform in networks, not just teams.

Our offer:
The successful candidate will work within “The Excellent Ideas Programme” that was created by the University of Würzburg to promote outstanding research within the leading-edge fields of research in its Faculties. We provide excellent technical equipment that allows you to further develop and apply a technology which is highly beneficial for your later career in academia or industry. The Programme is a joint effort of the Biocenter of the University of Würzburg and the Rudolf Virchow Center and embedded in the current excellence initiatives and research clusters. Hence, a stimulating collaborative research environment with multiple excellent research groups is provided. As a doctoral researcher you will be part of the Graduate School of Life Sciences of the University of Würzburg and the salary for this temporary position is commensurate with training and experience according to the Collective Agreement for the Public Service of German Federal States TV-L. Disabled applicants will be preferentially considered in case of equivalent qualifications. The position can start immediately or upon mutual agreement.

Contact:
Applicants are expected to include a brief cover letter describing previous research experience, interests and motivation, CV, the contact details of two references as well as a list of publications. Please submit the application as a single pdf file (no more than 10 MB) via email to Hans.Maric@virchow.uni-wuerzburg.de, subject: “Fluorescent Probes”, until 22nd of March. Review of applications will begin immediately.
Send application to
Dr. Hans Michael Maric
Department of Biotechnology and Biophysics
Rudolf Virchow Center for Experimental Biomedicine
University of Würzburg
Josef-Schneider-Straße 2, Haus D15
D - 97080 Würzburg
Hans.Maric@virchow.uni-wuerzburg.de
While applying for the job please refer to jobvector and use the following reference number: GSLS-1801

About University of Würzburg, Graduate School of Life Sciences

The Graduate School of Life Sciences (GSLS) Interdisciplinary research training is the key to the success of tomorrow's life scientists. The University of Würzburg provides for a world class environment of research institutions , which have a long standing and successful tradition of co-operation across faculties. The GSLS results from a common initiative of the Faculties...

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