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preparation and performing of experiments using primary cell cultures: preparation of primary neuronal cultures, use of fluorescence microscopes, western blotting and cell-based assays
Your key responsibilities
Cultivation/banking of human iPSCs and directed differentiation of human iPSCs towards neuronal lineages
Support high content drug screening campaigns
Support development of novel differentiation methods...
Support ongoing CRISPR screening and target validation activities
Establish and optimize workflows for generation of CRISPR mediated loss of function models
Establish and optimize cellular assays for genetic screening and target validation...
Contribute to projects using your assay development expertise
Move screening projects forward by establishing phenotypic or transcriptomic screening assays using, for example, disease relevant cellular models, reporters and/or CRISPR technology...
Planning, execution and interpretation of cell based assays
Evaluations of novel Anticalin proteins and drug candidates in cell assays
Characterization of functional activity of drug candidates (proliferation,...
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