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PhD position (Doktorand, m/w)

 Universitätsklinikum Düsseldorf  Düsseldorf
The Institute of Pathology of the Heinrich-Heine University of Düsseldorf (Director: Univ.-Prof. Dr. Irene Esposito) offers a
PhD position (Doktorand, m/w)
within the collaborative research project SFB 974 “Kommunikation und Systemrelevanz bei Leberschädigung und Regeneration”.
The group of Prof. Esposito investigates the molecular mechanisms of epithelial-stroma interactions in pancreatic and liver regeneration with different in vitro and in vivo methods. In this project, the impact of extracellular molecules on progenitor cell expansion and proliferation during liver regeneration will be analyzed. Knock-out mouse models will be employed to assess the composition and functional relevance of the microenvironmental niche. Signaling pathway analysis will disclose the influence of the extracellular matrix on epithelial cell behavior and pave the way for the development new targeted-treatment options in liver diseases.

Your profile:
  • Master degree/Diploma in Biosciences/Veterinary Medicine or related fields, preferably with background knowledge in molecular biology and mouse genetics.
  • High flexibility and strong motivation to perform research in an academic environment
  • Ability to work independently and as a part of a an international team
  • Excellent English communication skills (written and spoken)
  • Experience in mouse handling, cell culture, cell biology and molecular biology techniques
  • Experience in histopathology, stem cell biology, epigenetics and bioinformatics is a plus

Our offer:
  • An interesting and challenging task in a creative, young and dynamic research group
  • A friendly and multidisciplinary research environment
  • A high potential for your individual development
  • State of the Art facilities and cutting edge techniques
  • Salary according to the German collective labor agreement (TV-L 13, 65%)
  • Temporary contract until 31.12.2019 with possibility of extension

Starting Date: As soon as possible

The contract will be affiliated with the Heinrich-Heine-University of Düsseldorf.
The application in English or German language should include an application letter, CV, high school diploma, university diploma and list of courses, summary of the thesis and two letters of recommendation or contact information of two referees.
Female candidates are encouraged to apply; they will be given preference in cases of equal aptitude, ability, and professional achievements unless there are exceptional reasons for choosing another applicant.
Applications from suitably qualified severely disabled persons or disabled persons regarded as being of equal status according to Book IX of the German Social Legal Code (SGB – Soziales Gesetzbuch) are encouraged to apply. Disabled applicants will be given preferential consideration in the case of equal aptitude.
For administrative reasons we cannot return applications. In submitting your application, you give your consent to the retention of the application documents by the University Hospital of Düsseldorf. 
Questions regarding the project or the application can be addressed to
Please send your application including all relevant documents within 3 weeks from the publication of this announcement to:
Universitätsklinikum Düsseldorf
D 01.2.1 – Kennziffer:  71E/17, Moorenstr. 5, D-40225 Düsseldorf
How to apply:
Bitte richten Sie Ihre schriftliche Bewerbung an die angegebene Adresse.
Send application to
Universitätsklinikum Düsseldorf
D 01.2.1 – Kennziffer:  71E/17, Moorenstr. 5, D-40225 Düsseldorf
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