PhD Position in the field of Microalgal Molecular Biology

We offer                               
1 PhD Position (36 months)
in the field of
Microalgal Molecular Biology
within a DFG-funded research project. The project start is scheduled for 05/2016. Microalgal cells are constantly challenged by a fluctuating availability of carbon sources and light, which requires an adjustment of the light-harvesting antenna associated with photosystem II (LHCII). We identified the cytosolic translation repressor NAB1 as a key factor implicated in long-term acclimation responses, which target the antenna of Chlamydomonas reinhardtii. NAB1-mediated control of LHCII protein synthesis is fine-tuned on various levels, including the activation/repression of its nuclear promoter and the modulation of repressor activity based on protein S-nitrosylation. The PhD project will be dedicated to the elucidation of intracellular signaling mechanisms controlling NAB1 promoter activity and its repressor activity via chloroplast signals. Specifically, intended work will include the identification of transcriptions factors binding the NAB1 promoter and an analysis of the redox-crosstalk between chloroplast and cytosol that regulates the S-nitrosylation of NAB1. Furthermore, NAB1 will be used as a tool to characterize the interconnection between short- and long-term light acclimation mechanisms. The project includes research visits at the laboratory of Dr. Stephane Lemaire at the CNRS/Paris.   

Your qualifications:
  • Excellent Master degree or equivalent in Biology, Molecular Biology or Biochemistry
  • Strong background in protein biochemistry (protein purification techniques; MS-based protein identification) and molecular biology (cloning; gene knock-down techniques; mRNA/protein quantification)
  • Good command of the English language and high level of motivation
Your benefits:
  • The excellent infrastructure of the Center for Biotechnology at Bielefeld University with a superb working environment in which you have great opportunities to develop your ideas and accomplish your scientific goals in an international research group.
  • The participation in workshops and conferences.
Bielefeld University is committed to support equal opportunity; we encourage applications from qualified women and persons with disabilities.
Your application:
Please send CV (including transcripts & certificates), personal statement of research background & motivation and the name and contact details of two referees as one pdf document per email to:

Prof. Dr. Olaf Kruse, Bielefeld University; Dep. of Biology/CeBiTec; Chair of Algae Biotechnology & Bioenergy;

Application deadline is 15.05.2016.

How to apply:
Please send CV (including transcripts & certificates), personal statement of research background & motivation and the name and contact details of two referees as one pdf document.
Send application to
Prof. Dr. Olaf Kruse
Bielefeld University
Dep. of Biology/CeBiTec
Chair of Algae Biotechnology & Bioenergy
While applying for the job please refer to jobvector and use the following reference number: 01052016

About Universität Bielefeld

Bielefeld University was founded in 1969 with an explicit research assignment and a mission to provide high-quality research-oriented teaching. Today it encompasses 13 faculties covering a broad spectrum of disciplines in the humanities, natural sciences, social sciences, and technology. With about 22,000 students in 108 degree courses and about 2,750 staff members (including 264 professors and...

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