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PhD position (m/f) in Molecular Microbiology/Infection Biology

Workscope: Research Associate

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The strictly intracellular bacterial pathogens Chlamydiae are of great medical importance as they cause numerous diseases including sexually transmitted diseases and trachoma, the leading cause of blindness in the third world. Furthermore C. pneumoniae infection is associated with lung cancer. Chlamydiae highjack the eukaryotic cytoskeleton to facilitate invasion, replication and dissemination. While the role of the actin cytoskeleton during the chlamydial infection has been studied, the function of the host´s microtubule cytoskeleton is not understood. In this project, we will identify and characterize chlamydial proteins that regulate the microtubule cytoskeleton and determine their role in the infection process. As C. pneumoniae is not genetically accessible, the eukaryotic model yeast S. pombe will be used as a tool to identify chlamydial proteins that modulate the microtubule cytoskeleton.

The PhD position is funded by the Deutsche Forschungsgemeinschaft for 3 years and is available immediately at the Institut für funktionelle Genomforschung der Mikroorganismen at the Heinrich-Heine-Universität in Düsseldorf (http://www.hhu.de). The successful applicant holds a Master´s degree or equivalent in Biology or a related field. Previous experience with molecular biology, cell culture, yeast genetics and/or microscopy would be an advantage. A pronounced interest in research and the ability to work autonomously while being part of a team is expected.


Contact detail

How to apply:
Please send your application including cover letter, CV and the names of 2 referees as a single PDF file to sekretariat.fuge@uni-duesseldorf.de. Closing date is 4 September 2015.
Send application to
Please contact Prof. Fleig (fleigu@hhu.de) or Prof. Hegemann (hegemann@hhu.de) for further information on the position and the project.

Job profile

Working hours
Contract duration
Type of job
PhD Project
Work experience
job experience is not required
Germany (Nordrhein-Westfalen)
Working place
40225 Düsseldorf
Area of expertise
Biology & Life Sciences