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PhD-student (m/f) in mitochondrial architecture

Workscope: Research Associate

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The Research Group Mitochondrial Structure and Dynamics (head: Prof. Stefan Jakobs) at the Max Planck Institute for Biophysical Chemistry and at the University of Göttingen has an open position for
 
one PhD-student (m/f) in mitochondrial architecture
 
Who we are:
The research at the Max Planck Institute (MPI) for Biophysical Chemistry in Göttingen encompasses a wide spectrum of scientific topics and techniques. Of central concern are the mechanisms by which cells, organelles and biomolecules fulfill their manifold tasks. Ultra-high-resolution microscopy, nanotechnology, nuclear magnetic resonance spectroscopy, mass spectrometry and computer simulation are employed to delve ever-further into the nanocosmos of living cells.
The research group Mitochondrial Structure and Dynamics is investigating the mechanisms by which inner-mitochondrial architecture is determined and maintained. We are using a wide variety of experimental approaches that include molecular and biochemical tools, in particular electron and advanced super-resolution light microscopy, as well as live-cell imaging microscopy. Our group offers an outstanding and unique scientific setting with lot of individual freedom and possibilities for individual development as well as a vibrant working environment.
 
Who you are:
You are a highly motivated and curiosity driven biologist/biochemist/biophysicist who wants to work in a multidisciplinary team of physicists, chemists and biologists on the cell biology of mitochondria. You should hold an excellent university degree in biology, biochemistry, biophysics or a related discipline. Profound knowledge of (super‑resolution) light microscopy and/or molecular biology and/or cell biology is of advantage.
 
What your project will be about:
The aim of this project is to study the function of the mitochondrial multi-protein MICOS complex that maintains cristae junctions and is required for the intricate folding of the mitochondrial inner membrane.  The major model systems will be cultivated human cells and budding yeast. You will analyze the composition, dynamics and function of MICOS using a wide array of methods including biochemistry, super‑resolution microscopy, and quantitative immuno-gold electron microscopy. The project is part of a larger research consortium (SFB 1190).
 
The Max Planck Society is trying to increase the percentage of women on its scientific staff and strongly encourages applications from qualified women. It is also committed to employing more disabled persons and especially encourages them to apply.
Please send your application by E-mail (as a single PDF, not more than 5 MB) and do not hesitate to contact us if you have any further questions regarding the project and position.
 
Important note: the applicant must be able to come to Göttingen for a personal interview.
 
Please send inquiries and applications to
Dr. Peter Ilgen
Email: pilgen@gwdg.de
www.mitoweb.de
 
References:
Große et al. (2016), EMBO J 35 (4), 402-413
Jans et at. (2013), PNAS 110 (22), 8936-8941
Grotjohann et al. (2011), Nature 478, (7368), 204-208
 

Contact detail


How to apply:
E-mail only (as a single PDF, not more than 5 MB)
Send application to
Dr. Peter Ilgen
Email: pilgen@gwdg.de
www.mitoweb.de

Job profile


Working hours
Full-Time
Contract duration
Temporary
Type of job
PhD Project
Work experience
job experience is not required
Region
Germany (Niedersachsen)
Working place
37077 Göttingen
Area of expertise
Biology & Life Sciences
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