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PhD student position: Characterization of a novel mouse model of mucous membrane pemphigoid

PhD student position:
Characterization of a novel mouse model of mucous membrane pemphigoid
Mucous membrane pemphigoid (MMP) is a subepidermal blistering autoimmune skin disease that is characterized by the predominant involvement of mucous membranes. Recently, we have developed a novel mouse model for this disease by the transfer of antigen-specific antibodies in adult mice. The aim of the project is to further characterize the effector functions that lead to tissue destruction in the neonatal mouse model for MMP and to explore novel therapeutic targets in this model. The work will involve protein chemistry including molecular biology, expression and purification of proteins, Western blotting, ELISA, RT-PCR, immunohistochemistry, direct and indirect immunofluorescence microscopy, cell culture, and experiments with the mouse model. The position is integrated in an international team of post docs, PhD students, and technicians that all work on different aspects of autoimmune blistering diseases. You will work in the lab group of Prof. Enno Schmidt, MD, PhD, and be integrated in the DFG-funded Research Training Group 1727 Modulation of Autoimmunity. We are looking for a candidate that is highly motivated and would like to join our international team. The position is available starting March 1st, 2016 for initially 12 months with prolongation to three years being anticipated.
Who you are:
  • Self-motivated, creative and detail-oriented with excellent problem-solving skills
  • Have teamwork competency but can also work highly independently
  • Preferably have immunology experience
  • Have good written and oral communication skills in English
  • Have a strong passion for science
We offer:
  • Salary in accordance with German standards
  • Individualized supervision and mentoring
  • Excellent research environment
  • Integration in the Research Training Group 1727 Modulation of Autoimmunity.
  • Your full CV
  • A cover letter outlining your qualification for this position
  • A list of your methods and techniques
  • Reference letter
via e-mail to Dr. Franziska Schulze (FranziskaSophie.Schulze@uksh.de), Lübeck Institute of Experimental Dermatology (LIED), AG Schmidt, University of Lübeck, Lübeck, Germany (www.lied.uni-luebeck.de).
Applications will be reviewed until the position is filled.
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