A PhD Position on "Structural and biochemical characterization of protein ubiquitylation

 Universität Würzburg  Würzburg
A PhD Position on “Structural and biochemical characterization of protein ubiquitylation” is available in the group of Prof. Dr. Schindelin
 
The covalent modification of target proteins with ubiquitin serves a variety of important cellular responses. In humans ubiquitin is attached to target proteins via a hierarchical cascade of two ubiquitin activating enzymes (E1), dozens of ubiquitin conjugating enzymes (E2) and several hundred ubiquitin ligases (E3). The Schindelin lab is interested in E1 enzymes (Lee and Schindelin, Cell 134, 268-278 (2008); Schäfer et al., Acta Cryst D70, 1311-1320 (2014)), a multi-subunit E3 ligase and the AAA ATPase p97, which is a key player in the ubiquitin-proteasome system (Hänzelmann and Schindelin, Structure 24, 127-139 and 140-147, 2016).
 
Highly motivated candidates with a Masters (or equivalent) degree in biochemistry, molecular biology, biophysics or chemistry and a keen interest in structural biology, biochemistry, and biophysics are strongly encouraged to apply. Successful applicants must be able to work independently and as part of an international team. Previous experience in one of the following areas, structural biology (X-ray crystallography or electron microscopy), biochemistry or biophysics, is required.
 
Interested candidates should E-mail an application including a cover letter detailing their interests and expertise, their CV, transcripts, and the contact information of at least two references. The PhD students will be part of the Graduate School of Life Sciences (http://www.graduateschools.uni-wuerzburg.de/life_sciences). Salary will be according to the collective bargaining agreement (TV-L). Disabled applicants will be preferentially considered in case of equivalent qualifications.
 
For further information and to apply please contact:
Prof. Dr. Hermann Schindelin
Rudolf-Virchow-Zentrum für Experimentelle Biomedizin
Universität Würzburg
Josef-Schneider-St. 2 / Haus D15
D-97080 Würzburg
Germany
E-mail: teresa.frank@virchow.uni-wuerzburg.de
 
How to apply:
per Mail
Send application to
Prof. Dr. Hermann Schindelin
Rudolf-Virchow-Zentrum für Experimentelle Biomedizin
Universität Würzburg
Josef-Schneider-Str. 2 / Haus D 15
D-97080 Würzburg
Germany
E-mail: teresa.frank@virchow.uni-wuerzburg.de
While applying for the job please refer to jobvector and use the following reference number: 10/2016

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