PhD position at Chair for Molecular Animal Breeding and Biotechnology, LMU Munich

The Chair for Molecular Animal Breeding and Biotechnology - part of the excellence university LMU Munich - is highly interested in translational medicine. It uses genetic engineering for tailoring pigs as models of human diseases (diabetes, rare monogenic diseases) and as donors of cells, tissues and organs for xenotransplantation. The institute is located at two sites - in Munich-Oberschleißheim as well as at the Gene Center in Munich-Großhadern. It is closely associated with the Center for Innovative Medical Models (CiMM).

Activities and responsibilities

Within the Marie-Curie Innovative Training Network “DohART-NET“, the Chair for Molecular Animal Breeding and Biotechnology, LMU Munich, in close collaboration with MWM Biomodels GmbH, a spin-off company of LMU Munich, is looking for a highly motivated and skilled doctorate student (m/f/d). DohART-NET is focusing on effects of altered conditions during the periconceptional (PC) period and integrates pre-clinical (animal and stem cell models) and clinical studies.
The applicant will focus on studies of the effects of maternal diabetes on beta-cell function on the Islets of Langerhans of offspring from genetically (pre-)diabetic sows vs. healthy sows in clinical relevant large animal pig models, to assess the developmental programming effects of diabetes. The project comprises functional evaluation of beta-cell function in situ on pancreatic tissue slices as well as in vitro on isolated islets. This project encompass e.g. stimulated insulin secretion assays, ELISAs, immunofluorescent and immunohistochemical analyses of vibratome and microtome slices as well as RNA and protein analyses. Latest state-of-the-art technologies will be used.

Qualification profile

We are seeking a highly motivated doctorate student with:
  • An excellent Master’s degree (or equivalent) in biology, biotechnology or a related subject, or a background in veterinary medicine
  • Hands-on laboratory experience and strong interest in translational research
  • Solid knowledge in physiology and molecular biology
  • Practical sterile work and cell culture experience, together with molecular biology and imaging competencies, are strongly preferred but not mandatory

Eligibility (mandatory for funding)
  • Have not been awarded a PhD already
  • Less than 4 years research experience at the signature of the contract (counting from the time the Master’s degree has been obtained)
  • Spent less than 12 months in Germany in the 3 years prior to selection
  • Excellent knowledge of the spoken and written English language
  • Excellent communication and team working skills

We offer

The project implies a series of secondments at partner labs for additional training. The candidate will strongly benefit from a network of internationally recognized scientists and the participation of companies with relevant interests and expertise in the field.

The position will be on a temporary basis for a period of 36 months (Regular employment contract). The candidate will receive a Monthly Living Allowance plus a Mobility Allowance compliant with the applicable EC Marie Skłodowska-Curie Actions-ITN general conditions. The LMU is an equal opportunity employer. Disabled candidates with equal qualifications will be given preference.

Send application to

Please send your application (CV, letter of motivation, and relevant certificates) as a single PDF to kemter@genzentrum.lmu.de

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About Ludwig-Maximilians-Universität München

The Chair for Molecular Animal Breeding and Biotechnology - LMU Munich - is highly interested in translational medicine. It uses genetic engineering for tailoring pigs as models of human diseases (diabetes, rare monogenic diseases) and as donors of cells, tissues and organs for xenotransplantation. The institute is located at two sites - in Munich-Oberschleißheim as well as at the Gene Center...
More about Ludwig-Maximilians-Universität München