We are very sorry but it looks like you are using an outdated browser. We strongly recommend updating to a modern browser.
More information about your browser and how to update

PhD project: Decoding the functions of ubiquitin in the cellular response to DNA damage

This job ad is out of date. Find related Jobs here.

In the field of  “Ubiquitin signaling and mass spectrometry-based proteomics” the research group of Dr. Petra Beli offers the following PhD project: Decoding the functions of ubiquitin in the cellular response to DNA damage


Dynamic modification of proteins with ubiquitin after DNA damage has been shown to play a central role in all DNA repair pathways. In this regard, protein ubiquitination has most frequently been associated with the recruitment of DNA repair factors – many containing ubiquitin-binding domains –to DNA lesions and lesion flanking chromatin. The aim of this project is to identify the protein substrates and characterize the functions of selected nuclear ubiquitin ligases that are important for cellular survival after DNA damage. To this end, the prospective PhD student will employ a range of methods including mass spectrometry-based proteomics as well as advanced cell biological and biochemical methods such as flow cytometry, confocal microscopy, next generation sequencing and genome editing techniques.

We offer
• The possibility to work on a cutting-edge project using state-of-the-art technology in a highly motivated research team
• A stimulating, diverse and international research environment
• Advanced training opportunities
• A competitive stipend

Required qualifications
• Master or Diploma
• Motivation to solve complex biological problems
• Excellent communication skills

Starting date: 1 April 2016 or later
Duration of stipend: 3 years, with the possibility of extension
Deadline for registration (exclusively online via web form):  8 November 2015


Contact detail

How to apply:
Please apply exclusively via our online form at:
Send application to
For further questions and contact information please check our website:

Job profile

Working hours
Contract duration
Type of job
PhD Project
Work experience
job experience is not required
Germany (Rheinland-Pfalz)
Working place
55128 Mainz
Area of expertise
Biology & Life Sciences