Postdoc Biology, Biotechnology - Inflammation, Cancer Research (f/m/d)

The Division of Gastrointestinal Oncology is looking for a highly-motivated and ambitious

Postdoc in inflammation and cancer research (f/m/d)

with the working time of currently 38.5 hours/week. The salary is based on qualification according to TV-L 13 and is initially limited to 3 years with a long-term perspective.

 

Our working group is funded by an ERC Consolidator Grant and the newly founded SFB 1382.

We are investigating the role of programmed cell death pathways (apoptosis, necroptosis, ferroptosis, etc.) in acute and chronic liver disease with a focus on liver cancer. The work will be performed on different in vitro and in vivo models.

The PostDoc (f/m/d) will work on existing research projects in the aforementioned fields, develop new concepts and expand them in the future through third-party fundraising. In addition, it is expected to supervise medical and scientific doctoral students.

Your Profile

  • PhD in life sciences (Biology, Biotechnology, Biochemistry, Pharmacy or Human Biology/Molecular Medicine)
  • Practical experience in "in-vivo" mouse models (FELASA B or comparable qualifications)
  • Extensive experience in cell biological and molecular biological basic research, ideally with a focus on immunology (e.g. FACS)
  • Knowledge in the analysis of large data sets would be a benefit (e.g. Single Cell RNA Seq.)
  • Above-average commitment, willingness to work as part of a team in an international laboratory
  • Very good skills of English and German (in language and word) are expected

We offer

  • We offer a dynamic and interdisciplinary clinical and basic scientific environment and modern equipment.
  • A full-time position (38.5 h/week), initially to be filled for 3 years with the option of an prolongation.
  • Working in a young, committed and interdisciplinary team with interesting and exciting working objectives
  • Excellent development and training opportunities
  • Performance-related remuneration in accordance with TV-L13, depending on personal requirements including public service benefits
The RWTH Aachen with more than 40000 students and almost 6000 academic staff represents one of the largest universities in Germany.

The RWTH Aachen University is certified as a family-friendly university and offers a dual career program for partner hiring. We particularly welcome and encourage applications from women, disabled people and ethnic minority groups, recognizing they are underrepresented across RWTH Aachen University. The principles of fair and open competition apply and appointments will be made on merit.

 

Please send your complete application including a curriculum vitae, list of publications, a letter of motivation, all academic certificates and 2-3 references as well as the reference number: GB-P 20474 by November, 19th 2019 as 1 PDF file to Dr. Mihael Vucur (mvucur@ukaachen.de).

For further information please contact Prof. Dr. Tom Lüdde (tluedde@ukaachen.de) or visit our homepage (https://www.ukaachen.de/kliniken-institute/klinik-fuer-gastroenterologie-stoffwechselerkrankungen-und-internistischeintensivmedizin- med-klinik-iii/forschung/ag-luedde.html).

Literature:
Kather JN. et al. Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer. Nat Med. 2019.

Roy S. et al. microRNA 193a-5p Regulates Levels of Nucleolar- and Spindle-Associated Protein 1 to Suppress Hepatocarcinogenesis. Gastroenterology. 2018

Schneider AT. et al. RIPK1 Suppresses a TRAF2-Dependent Pathway to Liver Cancer. Cancer Cell. 2017.

Gautheron J. et al. The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance. Nat Commun. 2016.

While applying for the job please refer to jobvector and use the following reference number: GB-P 20474
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About Universitätsklinikum Aachen

Die Zukunftschancen des Universitätsklinikums Aachen und der Medizinischen Fakultät der RWTH Aachen beruhen auf der Verbindung von konsequenter Patientenorientierung, effizienter Lehre und innovativer Forschung. Diese geschieht in enger Kooperation mit den ingenieur- und naturwissenschaftlichen Disziplinen der Hochschule. Für die Erfüllung aller Ziele ist wirtschaftliches Handeln eine...
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