Scientist Bioinformatics – Machine Learning/ Biostatistics (f/m/d)

Immatics is a clinical-stage biopharmaceutical company active in the discovery and development of T-cell redirecting immunotherapies for the treatment of cancer. The Company’s transformative product candidates are Adoptive Cell Therapies and Bispecific TCR molecules. These products are directed against tumor targets that have been identified and validated by Immatics’ proprietary and world-leading XPRESIDENT® technology. Together with Immatics’ powerful TCR discovery technology XCEPTOR®, these two platforms allow a full range of cancer therapies to be developed. Immatics’ pipeline includes T-cell therapy programs based on the proprietary ACTolog®, ACTengine® and ACTallo® approaches, and several proprietary bispecific TCR (TCER®) and antibody molecules. Operating from Tuebingen, Munich and Houston, the Company has recognized that novel, better and safer targets are the key to developing future cancer immunotherapies, and it is Immatics’ mission to deliver the power of T cells to cancer patients. For more detailed information, visit

Activities and responsibilities

We are currently seeking full/part-time a Scientist Bioinformatics - Machine Learning/ Biostatistics (f/m/d) to support our R&D team to develop innovative immunotherapeutic products for cancer therapy. You will work in Tuebingen in a preclinical interdisciplinary environment with colleagues from Discovery, Immunology and Bioinformatics. Your analytical reasoning and your organizational skills will contribute to the team’s success. 

We offer a wide range of responsibilities in the field of statistical data analysis and machine learning. Your main responsibilities will include but are not limited to the following tasks: 
  • Training and evaluation of classification models on sequence and quantitative data of Immatics’ target discovery database XPRESIDENT® for the discovery of novel immunotherapeutic HLA peptides
  • Development of novel statistical models for target selection in precision medicine (Hilf et al. 2018, Nature)
  • Integrative analysis of a growing proprietary repository of transcriptome (RNA-seq) and
    HLA-peptidome data (LC-MS Mass spectrometry) for target identification (Zhang et al. 2018, Nat. Commun.)

Qualification profile

You hold a master’s degree or PhD in bioinformatics or have successfully completed a similar training and are proficient in at least one of the following programming languages: R, Python, Perl, Java. You have a profound statistical background and are experienced in machine learning methods. You have knowledge of working in a Linux environment and are familiar with basic biological concepts and bioinformatics tools.

We expect a high degree of independent working, analytical reasoning and that you take careful processing and documenting of your results for granted. You embrace rapidly changing requirements with an open mind and show a high degree of flexibility in an environment which is marked by a constant striving for excellence. Your motivation is driven by your passion for innovation and science. You approach tasks in a structured, reliable and foresighted manner, combined with an elevated level of individual responsibility, enthusiasm and strong social skills.


We are a committed and inspired team and cherish the collegial, highly motivated and family-friendly atmosphere within Immatics. Our culture allows for a high level of originality, independent thinking and initiative. We believe in supporting our employees’ professional and social skills: We enable them to join conferences and trainings as well as to enjoy our Immatics benefits – e.g. JobRad, Health Programs, childcare benefits, Company summer and winter events.

Send application to

If you’re interested in working for Immatics, please apply online and provide your application documents along with the relevant credentials and certificates. Mrs Annemarie Selbenbacher will answer initial questions at +49 89 125 03 98 33 (landline number Germany). Constares GmbH (Mrs Annemarie Selbenbacher) advises Immatics on this job posting.

While applying for the job please refer to jobvector and use the following reference number: jv-0205

About Immatics Biotechnologies GmbH

Immatics Biotechnologies GmbH   Immatics Biotechnologies GmbH ist ein unabhängiges biopharmazeutisches Unternehmen mit Sitz in Tübingen und München, das aktive Immuntherapien gegen Krebs entwickelt. Die therapeutischen Impfstoffe von immatics basieren auf Kombinationen mehrerer tumor-assoziierter Peptide (TUMAPs), die das Immunsystem gezielt gegen...
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