Scientist Biology, Biochemistry, Biophysics - Protein Engineering & Technology Scouting (m/f/d)

Pieris Pharmaceuticals (Nasdaq: PIRS) is a publicly-traded, clinical-stage biotechnology company with operations in Germany and the United States. Pieris specializes in the discovery and development of Anticalin® protein-based drugs to target validated disease pathways in a unique and transformative way. Our pipeline includes inhalable Anticalin proteins to treat respiratory diseases, immuno-oncology multi-specifics tailored for the tumor microenvironment, and a half-life-optimized Anticalin protein to treat anemia. Proprietary to Pieris, Anticalin proteins are a novel class of therapeutics validated in the clinic and by partnerships with leading pharmaceutical companies.

To strengthen our team in Hallbergmoos, we are looking for an experienced:

Scientist Protein Engineering & Technology Scouting (m/f/d)

Your Tasks

  • Design and generation of display libraries for Anticalin® selection
  • Proposal and execution of rational engineering strategies for Anticalin based mono- and multispecifics and fusion proteins
  • Responsible for bioinformatics and protein structure analyses
  • Proficient in implementing and applying software to design and optimize biologics such as MOE / Rosetta for protein modeling
  • Gathers and analyzes data to apply machine learning methods for protein engineering
  • Database management and support
  • Scouts for novel technologies
  • Collaborates with external industrial and academic partners

Our Requirements

  • PhD in life science or related area (biology, biochemistry, biophysics, biotechnology, bioinformatics) with 2+ years experience
  • Solid knowledge in protein folding, aggregation, structure and dynamics
  • Deep understanding of techniques to study protein-protein interactions and state-of-the-art atomic-resolution structure elucidation tools such as NMR, X-ray crystallography, cryo-EM
  • Understanding of different display technologies as well as scaffold and antibody technologies
  • Expertise in Scripting (e.g. Python) and Molecular Dynamics is a definite plus
  • Knowledge of DNA sequence analysis tools such as Geneious will be beneficial
  • Cross-disciplinary orientated as well as reliable and flexible team player
  • Imaginative personality with self-sufficient and communicative appearance
  • Strong analytical and problem solving skills
  • Precise and efficient operating
We are a fast-growing biotechnology company with approximately 130 employees at our sites in Freising (Greater Munich Area) and Boston (USA). We work in flat hierarchies with short decision-making paths and offer a working environment characterized by cooperation and innovation. Each of our employees participates in a bonus program based on the achievement of individual and company-wide goals. In addition, we offer each employee the opportunity to participate in a stock savings plan and a stock option program that allows employees to benefit directly from the company's success.

Numerous social benefits such as additional employer-financed company health insurance, free drinks, fruit baskets etc. as well as a bright, friendly and ultra-modern working environment with excellent technical equipment in our new company building in Hallbergmoos (from February 2020) round off our overall package. Creative employee events take place several times a year, as team spirit is essential for us. The joint creation of an innovative and participative corporate culture is an important concern for us.

While applying for the job please refer to jobvector

About PIERIS Pharmaceuticals GmbH

Pieris Pharmaceuticals (Nasdaq: PIRS) ist ein Biotechnologieunternehmen mit Standorten in Deutschland und den USA, welches sich auf die Erforschung und Entwicklung Anticalin®-basierter Medikamente spezialisiert hat. Zusammen mit unseren Partner leisten wir innovative Forschungsarbeit in den Bereichen Immun-Onkologie und Atemwegserkrankungen. Bei den proprietären Anticalin-Proteinen...
More about PIERIS Pharmaceuticals GmbH