Doctoral Researcher Bioprocess Engineer/ Bio-physicist (f/div/m)

The Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute –
(Leibniz-HKI, www.leibniz-hki.de) investigates the pathobiology of human-pathogenic fungi and identifies targets for the development of novel natural product-based antibiotics.

Activities and responsibilities

The research of the Microfluidics Group at the Bio Pilot Plant has been focused on the establishment of a droplet-based microfluidic strategy to exploit microbial diversity and screen with ultra-high throughput for bacteria producing novel natural products. As pioneers in the encapsulation and cultivation of cells and microorganisms in droplets, we are further developing our microfluidic platform to address all the details required for its effective application. To further expand the applicability of our technology and upgrade it with the latest innovations of ultrahigh throughput liquid handling, we initiated, under the frame of the Leibniz Science Campus InfectoOptics, an interdisciplinary cooperation project between the HKI Bio Pilot Plant, the Fraunhofer Institute for Applied Optics and Precision Mechanics IOF and the Leibniz Institute for Photonic Technologies IPHT.

The successful candidate will design, construct and optimize sample multiplexing and droplet deposition equipment for the established droplet microfluidic platform. Additionally, he/she will integrate advanced droplet analytical developed by the project partners into the platform. Work will take place in a dynamic and highly motivated group. Within the group, the Engineer will experience a strong support based on lively collaboration and friendly interaction between the interdisciplinary scientists and access to state-of-art equipment. In addition, the applicant will have all possibilities to realize own innovative ideas and develop new projects while contributing to the organization within the Microfluidics Group.

Qualification profile

  • A degree/experience in engineering, physics or related disciplines with basic knowledge of microfluidic principles and techniques
  • Strong interest in biological application of microfluidic techniques, enriching the multidisciplinarity of the group
  • Knowledge in electro-optical components for signal acquisition and processing
  • Large dataset analysis (MatLab, R studio, others)
  • Strong knowledge in design and building of optical constructs and troubleshooting
  • The candidate should embrace working in an international, interdisciplinary research team
  • Ability for team-oriented as well as creative and independent work
  • Very good communication skills in English
Preferred Skills
  • Experience in microfluidic research and/or flow cytometry, microsystems or biomedical engineering would be an advantage
  • Advanced programming skills in LabView, Arduino, C/C++ for microcontrollers
  • Specialized software knowledge (Zemax, Comsol, AutoCAD or other)

We offer

The research group is embedded in the outstanding scientific environment of the Beutenberg Campus providing state-of-art research facilities and a highly integrative network of life science and technical science institutes and groups. We offer excellent technical facilities, a place in a committed team, as well as strong scientific collaborations.

As a PhD candidate, the applicant will be a graduate student at Friedrich-Schiller-University Jena and benefit from the extended graduate training of the Jena Graduate Academy and the Jena School of Microbial Communication.

Salary is according to German TV-L (salary agreement for public service employees). As an equal opportunity employer the HKI is committed to increase the percentage of female scientists and therefore especially encourages them to apply. The position will be filled as soon as possible.

Send application to

Please contact

Prof. Dr. Miriam Agler-Rosenbaum | +49 3641 532 1120
Dr. Miguel Tovar | +49 3641 532 1495

While applying for the job please refer to jobvector and use the following reference number: HKI-19/2019

About Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie

The Leibniz-Institute for Natural Product Research and Infection Biology (HKI) identifies and investigates natural products produced by microorganisms, mainly fungi, to understand their role as mediators of biological communication and to use them for the elucidation of cellular processes. Furthermore, scientists at the Institute are interested in understanding the pathobiology of...
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