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Doktorandenstelle/PhD Position (Life Sciences)

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A 3-year PhD Position (E13, 65% ) is available in the department of Membrane Biochemistry at the Life & Medical Sciences Institute from the University of Bonn. The group's main research focus is on the structure and function of biological membranes (see also our website "membiol.uni-bonn.de").

This particular project has an emphasis on the mechanisms by which the Amyloid Precursur Protein (APP), which is involved in Alzheimer's disease, forms protein clusters in the plasma membrane. Applying a spectrum of modern imaging techniques (superresolution microscopy, TIRF microscopy and FRAP) it is planned to study how APP clustering in the plasma membrane is related to its processing by secretases.

The applicant should have graduated in biology/biochemistry or a related subject.

For general reading see:

Sieber, J.J., Willig, K.I., Kutzner, C., Gerding-Reimers, C., Harke, B., Donnert, G., Rammner, B., Eggeling, C., Hell, S.W., Grubmüller, H. and Lang, T. (2007). Anatomy and dynamics of a supramolecular membrane protein cluster. Science 317, 1072-1076 

Saka, S.K., Honigmann, A., Eggeling, C., Hell, S.W., Lang, T. and Rizzoli, S.O. (2014). Multi-protein assemblies underlie the mesoscale organization of the plasma membrane. Nat. Commun. 5, 4509

For special reading see:

Schreiber, A., Fischer, S. and Lang, T. (2012). The Amyloid Precursor Protein Forms Plasmalemmal Clusters via Its Pathogenic Amyloid-beta-Domain. Biophys. J. 102, 1411-1417

Contact detail

How to apply:
Please send your application by Email to:

Send application to
Prof. Dr. Thorsten Lang
E-Mail: thorsten.lang@uni-bonn.de
Telefon: 0228-73 62 823

Life & Medical Sciences Institute, Universität Bonn, Membrane Biochemistry Lab
Carl-Troll-Str. 31
53115 Bonn

Job profile

Working hours
Contract duration
Type of job
PhD Project
Work experience
job experience is not required
Germany (Nordrhein-Westfalen)
Working place
53115 Bonn
Area of expertise
Biology & Life Sciences