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Ph. D. Student Position

The Research Groups “Macromolecular Crystallography” (Dr. Vlad Pena) at the Max Planck Institute for Biophysical Chemistry and “Nucleic Acid Chemistry” (Prof. Dr. Claudia Höbartner) at the University of Göttingen invite applications for a joint

Ph. D. Student Position
“Structural and mechanistic studies of catalytic DNA molecules”
(Code Number 14-16)

Although DNA is mostly known as an information carrier, single stranded DNA molecules selected in vitro can catalyse a wide range of chemical reactions. Recently, we demonstrated that such a DNA enzyme (or deoxyribozyme) adopts an intricate 3D structure (Ponce-Salvatierra et al., Nature, 2016), just as RNA and proteins. The finding is important both with respect of the biotechnological and medical applications, as a well as the potential implication of DNA folds in organisms.

The goal of the current project is the mechanistic investigation of several DNA catalysts, as a mean to elucidate their reaction mechanisms, and to advance understanding the structural principles of complex DNA folds. The main tool of investigation is X-ray crystallography, complemented by biochemical functional assays.

Candidates should hold a Master’s (or equivalent) degree in Biochemistry, Molecular Biology or Chemistry, and have a strong interest in structural biology.
The position is funded in collaboration with the University of Göttingen and the successful candidate will have the chance to participate in one of several available interdisciplinary Ph.D. programs at the University of Göttingen.

The Max Planck Society is committed to increasing the number of individuals with disabilities in its workforce and therefore encourages applications from such qualified individuals.
Furthermore, the Max Planck Society seeks to increase the number of women in those areas where they are underrepresented and therefore explicitly encourages women to apply.

Applications should include a CV, a list of publications (if applicable) and contact names and addresses of one to three references familiar with the work of the candidate. Please submit all materials preferably in electronic form (as one single PDF file) via e-mail with reference to the code number 14-16 until September, 30th 2016  to

ausschreibung14-16@mpibpc.mpg.de

Max Planck Institute for Biophysical Chemistry
Research Group "Macromolecular Cryistallography"
Dr. Vlad Pena
Am Fassberg 11, 37077 Göttingen
Germany

Contact detail


How to apply:
Applications should include a CV, a list of publications (if applicable) and contact names and addresses of one to three references familiar with the work of the candidate. Please submit all materials preferably in electronic form (as one single PDF file) via e-mail with reference to the code number 14-16 until September, 30th 2016 to ausschreibung14-16@mpibpc.mpg.de
Send application to
ausschreibung14-16@mpibpc.mpg.de

Max Planck Institute for Biophysical Chemistry
Research Group "Macromolecular Crystallography"

Dr. Vlad Pena
Am Fassberg 11
D-37077 Göttingen

Job profile


Working hours
Full-Time
Contract duration
Temporary
Type of job
PhD Project
Work experience
job experience is not required
Region
Germany (Niedersachsen)
Working place
37077 Göttingen
Area of expertise
Biology & Life Sciences, Chemistry, Physics, Biotechnology
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