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PhD candidate in Infection Biology

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The Friedrich Loeffler Institute of Medical Microbiology at the University Medicine Greifswald is looking at the earliest possible date for a
PhD candidate in Infection Biology 
We are seeking a highly motivated and skilled candidate with an interest in basic research and infection biology. The aim of our research is to unravel survival strategies of bacterial pathogens in the host, but also to investigate innate immune mechanisms important to combat infection. We focus in our work on the important pathogen and intracellular model organism Burkholderia pseudomallei, the causative agent of melioidosis. The results of our work should lead to a better understanding of host pathogen interaction on a molecular level and thereby to better approaches in infection therapy and vaccination.
In previous work we investigated the role of various cytoplasmic protein complexes (inflammasomes) in the intracellular recognition of B. pseudomallei and subsequent activation of caspases (PLoS Pathog. 2014.10(3):e1003986). During the PhD project the role of these enzymes in inducing cell death mechanisms and inflammatory reactions during infection will be further investigated. This will also include further identification of B. pseudomallei factors involved in inflammasome activation of host cells. The appointee will learn and use different molecular, microbiological, cell biological as well as immunological approaches. Access to state-of-the-art OMICs technologies present at the University of Greifswald, will guarantee excellent study conditions.
The PhD candidate will be a member of the Research Training Group 1870 (RTG 1870) “Bacterial Respiratory Infections – Common and Specific Mechanisms of Pathogen Adaptation and Immune Defense” funded by the German Research Foundation (DFG). The interdisciplinary research programme will constitute an ideal training ground for young biomedical scientists. PhD students will benefit from a structured teaching programme including summer schools with international experts, young investigator meetings, laboratory courses, joint lectures and seminars, transferable skill modules and international scientific meetings. An optional student exchange programme will be offered that aims to broaden young researchers methodological skills and promote their integration into the international scientific community.
The University and Hanseatic City of Greifswald is located near the bay of Greifswald, which is part of the Baltic Sea between the islands of Rügen and Usedom and offers great recreational possibilities.
Unfortunately we cannot refund any travelling and accommodation costs.


Contact detail

How to apply:
Post or E-Mail
Send application to
Please direct applications (cover letter, CV, publication list) until 04th September 2015 to:
Prof. Dr. Ivo Steinmetz
Friedrich Loeffler Institute of Medical Microbiology
University Medicine Greifswald
Martin-Luther-Str. 6
17475 Greifswald


Job profile

Working hours
Contract duration
Type of job
PhD Project
Work experience
job experience is not required
Germany (Mecklenburg-Vorpommern)
Working place
17489 Greifswald
Area of expertise
Biology & Life Sciences