PhD in Bioinformatics: Epigenetics of Human Blood Cells

The group "Stem Cell Biology and Cellular Engineering“ at RWTH Aachen University Medical School is offering a position for a Ph.D. student (m/f). 

Focus of this project is the development of epigenetic methods for blood counts based on DNA methylation data. The analysis of the composition of cell types in blood is one of the most frequently used diagnostic test. We have established a simple method to determine blood counts based on DNA methylation at specific sites in the genome (Frobel et al., Clin Chem. 2018. doi: 10.1373/clinchem.2017.279935). This method shall now be further developed and validated.

Activities and responsibilities

DNA methylation profiles will be analyzed in hematopoietic subsets with different sequencing approaches. This data needs to be evaluated and compiled into deconvolution algorithms. This project will be funded by a VIP+ project (BMBF) with the perspective to generate an in vitro diagnostic tool that may be further marketed.

Qualification profile

We are looking for a highly motivated and ambitious PhD student with a strong background in bioinformatics and epigenetics. Experience in wet lab biology would be advantageous. Willingness for teamwork, the ability to work independently, and excellent English language skills are a prerequisite.

Benefits

We offer a highly interactive and well equipped environment in a team with international partners, a broad spectrum of methods, and a highly relevant topic. (homepage: www.stemcellbiology.ukaachen.de)
 
Funding is available for at least three years (65% TV-L E13).


The RWTH Aachen University is certified as a family-friendly university and offers a dual career program for partner hiring. We particularly welcome and encourage applications from women, disabled people and ethnic minority groups, recognizing they are underrepresented across RWTH Aachen University. The principles of fair and open competition apply and appointments will be made on merit.

Send application to

Your application should include a cover letter which specifically emphasizes your interest in our work (preferably in English), CV, and copies of the most important certificates. For additional questions please contact Prof. Dr. Dr. Wolfgang Wagner. Your application should be send by Email until December 21st, 2018 (wwagner@ukaachen.de).

We are looking forward to your application!

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About University of Aachen Medical School

The University Hospital Aachen (UKA) combines in its singularity all mechanisms of supplying the patient, the entire medical faculty and the dentistry under one roof. In this enormous building is a place for the common research of engineers, scientists and physicians. Further information for the research field "Stem Cell Biology and Cellular Engineering":...

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