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PhD in Liver physiology and toxicology

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About five million individuals are affected by liver diseases in Germany, and the causes of these diseases often remain unknown. The Federal Ministry of Education and Research (BMBF) has recently funded a research network entitled ‘Systems Medicine of the Liver’ aimed at better understanding the etiology and progression of liver disease. Within this project, the PhD positions described below are available at the IFADO (Leibniz Research Centre) in Dortmund, Germany: http://www.ifado.de/toxikologie/. The successful candidates will work within an interdisciplinary network of molecular biologists, bioinformaticians, systems biologists and physicians. We are looking for highly motivated PhD candidates who are aiming for as successful career in science. The PhD student will be integrated into an international and successful research network. 

PhD for Liver physiology and toxicology

 Aim of the project is to establish an in vitro system to predict liver toxicity of pharmaceuticals and chemicals. There is a high need of such predictive systems, since hepatotoxicity is the most frequent reason for drug withdrawal from the market. The study will compare molecular mechanisms leading to liver toxicity in cultivated hepatocytes and the liver in vivo. Techniques will include genome-wide expression profiling, imaging (confocal and two-photon microscopes), cultivation of primary hepatocytes and systems biology methods. The candidate will work in an international network of experts and we offer good conditions for a successful career in science.
We are looking for a highly motivated PhD candidate, with a background in biology, chemistry, pharmacy or similar fields. who enjoys experimental work. 


Contact detail

How to apply:
application, cv , a letter of motivation, and the name and contact information of two referees.

IfADo is an equal opportunity employer, and does not discriminate on gender, race, colour, religion, national origin, disability, or age in its programs and activities. 
Send application to
If you are interested, please send your application and CV to:

Prof. Dr. Jan G. Hengstler (Hengstler@ifado.de)


Silke Hankinson (Hankinson@ifado.de) Phone: +49 231 1084-349

Job profile

Working hours
Contract duration
Type of job
PhD Project
Work experience
job experience is not required
Germany (Nordrhein-Westfalen)
Working place
44139 Dortmund
Area of expertise
Biology & Life Sciences