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PhD position in Biochemistry: Light-activated membrane organization and receptor clustering

PhD position
“Light-activated membrane organization and receptor clustering”
The Institute of Biochemistry (www.biochem.uni-frankfurt.de) of Goethe University Frankfurt, Germany, offers a PhD (E13 TV-G-U, 65%) for a three-year period.
Our project aims at a light-triggered control of the lateral membrane organization of receptors in live mammalian cells via novel optochemical and optogenetic tools. Cell surface receptors play a key role in multiple cellular processes and many diseases have been linked to a plethora of receptor dysfunctions. Whereas many scientific teams investigate most steps in receptor signaling, their dynamics in the plasma membrane is poorly understood. It is thus necessary to conceive new techniques to study the lateral receptor trafficking and clustering with highest spatiotemporal resolution.

Your part will be to trigger clustering by light, followed by diverse analysis methods such as fluorescence and single molecule imaging. You will work in a lively, international, and forefront-equipped research environment, embedded in the Life Science Campus Riedberg, Goethe University.

For this challenging project, we expect a candidate with strong interest in live cell imaging and light-triggered processes burning to develop new approaches for light-triggered manipulation in living cells. By the way, you should have a Master´s/diploma degree in biochemistry, biology, chemistry, or life sciences.

Women are specifically invited to apply within the frame of the equal opportunity program.
The Goethe University is committed to give preference to handicapped candidates with equivalent qualifications. The limitation of the contract is based upon the regulations of the “Wissenschaftszeitvertragsgesetz” in conjunction with the “Hessischen Hochschulgesetz”.

Then submit your CV and further information per e-mail to:
Prof. Dr. Robert Tampé
Institute of Biochemistry
Max-von-Laue Str. 9 
60438 Frankfurt/Main
Deadline: January 31st 2016
Kollmannsperger et al. (2015) Nature Commun, in press.
Wieneke et al. (2015) Angew Chem Int Ed Engl. 54, 10216-9.
Wieneke et al. (2014) J Am Chem Soc 136, 13975-78.
Labòria et al. (2013) Angew Chem Int Ed Engl. 52, 848-53.

Contact detail

How to apply:
Email application: application@biochem.uni-frankfurt.de
Send application to
Prof. Dr. Robert Tampé
Institute of Biochemistry
Max-von-Laue Str. 9 
60438 Frankfurt/Main

Job profile

Working hours
Contract duration
Type of job
PhD Project
Work experience
job experience is not required
Germany (Hessen)
Working place
60438 Frankfurt
Area of expertise
Biology & Life Sciences