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PhD position in Biochemistry: “Structure and Mechanism of the Antigen Translocation Complex”

PhD position in Biochemistry:
Structure and Mechanism of the Antigen Translocation Complex”

The Institute of Biochemistry (www.biochem.uni-frankfurt.de) of Goethe University Frankfurt, Germany, offers a PhD position (E13 TV-G-U, 50 - 65%) for a 3-year period.

Our project aims at a central machinery in adaptive immunity, which delivers proteasomal degradation products into the ER for loading of MHC class I molecules. These processes play a fundamental role in the immune recognition and escape strategies of virally or malignantly transformed cells.

Your part will be to investigate mechanistic and structural aspects of multi-subunit complexes by diverse methods such as cryo-EM, X-ray analysis and single-molecule techniques. You will work in a lively, international, and forefront-equipped research environment, embedded in the Life Science Campus Riedberg, Goethe University.

For this challenging project, we expect a candidate with strong interest in cell and structural biology. By the way, you should have a Master degree in biochemistry, biology, chemistry, or life sciences.

Women are specifically invited to apply within the frame of the equal opportunity program.
The Goethe University is committed to give preference to handicapped candidates with equivalent qualifications. The limitation of the contract is based upon the regulations of the “Wissenschaftszeitvertragsgesetz” in conjunction with the “Hessischen Hochschulgesetz”.

Captivated? Then submit your CV and further information per e-mail to: Prof. Dr. Robert Tampé Institute of Biochemistry, Max-von-Laue Str. 9, 60438 Frankfurt/Main. (application@biochem.uni-frankfurt.de)


References:

1) Blees et al. (2015) Sci Rep 5, 17341.  http://dx.doi.org/10.1038/srep17341

2) Kim et al. (2015) Nature 517, 396-400. http://dx.doi.org/10.1038/nature13872

3) Fischbach et al. (2015) Nature Commun 6, 6199. http://dx.doi.org/10.1038/ncomms7199

4) Lin et al. (2014) PLoS Pathogens 10, e1004554. http://dx.doi.org/10.1371/journal.ppat.1004554

5) Grossmann et al. (2014) Nature Commun 5, 5419. http://dx.doi.org/10.1038/ncomms6419

Contact detail


How to apply:
Captivated? Then submit your CV and further information per e-mail to: Prof. Dr. Robert Tampé Institute of Biochemistry, Max-von-Laue Str. 9, 60438 Frankfurt/Main. (application@biochem.uni-frankfurt.de)
 
Send application to
per e-mail: application@biochem.uni-frankfurt.de

Job profile


Working hours
Part-Time
Contract duration
Temporary
Type of job
PhD Project
Work experience
job experience is not required
Region
Germany (Hessen)
Working place
60438 Frankfurt
Area of expertise
Biology & Life Sciences, Chemistry
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