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PhD position in Molecular Tumor Biology (Würzburg)

Our Goal:
Our central research topic is the role of the Myc oncoprotein in cancer biology. We want to understand, how Myc functions in health and disease on a molecular level. We use new techniques like NGS (Next generation sequencing) to gain whole-genome information about Myc induced cellular changes (RNA-Seq, Gro-Seq) and Myc binding (ChIP-Seq). Recently we characterized the binding profile of Myc (Walz et al., Nature 2014) and its binding partner Miz1 (Wolf et al, Nature Communications 2013) in several systems. Overall, we could identify new mechanisms, which can explain Myc´s important role in tumorigenesis (Wolf et al, Trends in Cell biology, 2015). In the future we want to analyze how Myc communicates with the RNA polymerases to regulate transcription. The ultimate goal is the development of strategies how Myc´s function in tumors can be blocked.

Requirements:
Motivated applicants should have a strong background in molecular biology and biochemistry and should have excellent lab skills. An interest in bioinformatics is needed, as sophisticated analyses are part of the project, however previous knowledge is not necessary. Applications from severely handicapped persons with basically similar qualification will be given priority. Salary will be according to TV-L (E13, 65%).

We offer:
The successful candidate will be part of a new research group (Dr. Elmar Wolf) located within the institute of Biochemistry and Molecular Biology headed by Prof. Martin Eilers. This constellation provides both, tight supervision in a well-thought-out project and the scientific background of one of the world-leading institutes working on Myc. The institute provides excellent equipment allowing state-of-the-art experiments and the candidate will learn techniques, which are highly beneficial for her or his later carrier in academia or industry. The PhD-position will be embedded in the graduate school of life science, ensuring an efficient and speedy PhD process.

Contact:
Applications (brief cover letter describing previous research experience and interests, CV, certificates and the contact details of two referees) should be sent per e-mail (subject: ”PhD Myc”) until 25.08.2015 to: elmar.wolf@biozentrum.uni-wuerzburg.de
 
Further information:
http://www.pch2.biozentrum.uni-wuerzburg.de/research_groups/ag_wolf/
Dr. Elmar Wolf, Biozentrum der Universität Würzburg, Lehrstuhl für biochemie und Molekularbiologie, Am Hubland, 97074 Würzburg

Contact detail


How to apply:
Applications (brief cover letter describing previous research experience and interests, CV, certificates and the contact details of two referees) should be sent per e-mail (subject: ”PhD Myc”) until 25.08.2015 to: elmar.wolf@biozentrum.uni-wuerzburg.de
Send application to
Dr. Elmar Wolf, Biozentrum der Universität Würzburg, Lehrstuhl für biochemie und Molekularbiologie, Am Hubland, 97074 Würzburg, elmar.wolf@biozentrum.uni-wuerzburg.de

Job profile


Working hours
Full-Time
Contract duration
Temporary
Type of job
PhD Project
Work experience
job experience is not required
Region
Germany (Bayern)
Working place
97074 Würzburg
Area of expertise
Biology & Life Sciences, Human medicine, Biotechnology
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