PhD position in mitochondrial cell biology

The Osman lab at the Department of Cell and Developmental Biology at the University of Munich (LMU) is recruiting a PhD student, to start earliest on August 1st of 2019.

Activities and responsibilities

We are a young lab that is interested in the fundamental but poorly understood question of how cells maintain and correctly organize their mitochondrial genomes. Since the mitochondrial genome is essential for energy production in cells, failure in the maintenance of a functional mitochondrial genome has dire consequences that can lead to diseases or aging. Elucidation of the mechanisms that ensure maintenance and organization of error-free mitochondrial genomes therefore holds the key to understand the cause for such diseases or aging phenotypes.
Our lab combines the model organism S. cerevisiae with a wide spectrum of state-of-the-art approaches to tackle these questions, which include:
  • Multi camera live-cell-microscopy with high temporal resolution to examine the dynamics of the mitochondrial genome
  • Super-resolution microscopy
  • Computational image analysis of microscopy data
  • Next-generation sequencing of mitochondrial DNA
  • Biochemical approaches combined with mass spectrometric analyses
  • Yeast genetics

Qualification profile

We are looking for highly motivated students holding an excellent Master’s degree (or equivalent) to join our group. Experience in one of the following areas is desirable: microscopy image analysis, cell biology, yeast genetics

The position comes with teaching obligations of 2.5 SWS that are to be fulfilled by supervising practlical courses of bachelor or master students.

Benefits

Our research group is part of the cell- and developmental biology department, which not only offers high-end instrumentation and laboratory equipment but also a highly interactive and international research environment.

Send application to

To apply, please send your application materials, including a motivation letter, your CV, and names of two referees in a single pdf file to Christof Osman (osman@bio.lmu.de), who can also supply further information about this position.

While applying for the job please refer to jobvector

About Ludwig-Maximilians-Universität München, Osman Lab

The viability and function of every eukaryotic cell crucially depends on its supply with energy. The majority of this energy is generated in mitochondria in the form of ATP by multisubunit-complexes of the respiratory chain in a process known as oxidative phosphorylation. While most of the subunits of the respiratory chain complexes are encoded in the nuclear genome and are imported into...
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