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PhD positon: Genome Stability

The European Research Institute for the Biology of Aging (ERIBA) is a newly established institute at the University Medical Centre Groningen (UMCG). The mission of ERIBA is to better understand the molecular mechanisms that result in age-related decline and age-related diseases. We aim to develop novel strategies to prevent or combat age-related diseases and to provide evidence-based recommendations for healthy ageing. The research teams are working with different model systems and technology platforms and share their knowledge and expertise to accelerate discoveries. The ERIBA is housed in a new building and is part of the central UMCG campus in the vibrant university city Groningen in the north of the Netherlands.
 
We are currently looking for:
 
a PhD student
 
in the lab of Dr. Katrin Paeschke (Laboratory of nucleic acids structures and repair) we are looking for a highly motivated and determined candidate for a PhD position.
The PhD student will work on methods to analyze G-quadruplex structures and their biological function in vivo. Recently, it was shown that G-quadruplex structures can form within DNA and RNA and that specific proteins contribute to their regulation. Additionally, we have shown that G-quadruplex structures also challenge genome stability and induce mutations and deletions. In this project we will explore their action and their consequences in yeast and human cells. This work will extend studies that have been published recently (Paeschke et al, Cell 2012, Paeschke et al, Nature 2013).
 
You will be part of an international research team as part of the ERIBA Institute as well as of the UMCG. The ERIBA-UMCG offers an excellent research environment with ample possibilities for collaboration with both basic as well as clinical researchers and ERIBA-UMCG offers state-of-the-art facilities.
 
Requirements
  • MSc in a biomedical field
  • Experience with molecular and cellular lab skills.
  • Good English language skills.
  • A collaborative attitude.

Contact detail


How to apply:
per Email
Send application to
For more information see http://www.eriba.umcg.nl or contact Katrin Paeschke at k.paeschke@umcg.nl.
 

Job profile


Working hours
Full-Time
Contract duration
Temporary
Type of job
PhD Project
Work experience
job experience is not required
Region
Netherlands
Working place
9724 Groningen - NL
Area of expertise
Biology & Life Sciences
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