PhD Thesis: Unravelling the role of CENP-A in DNA damage response
Mathew, V., Pauleau, A. L., Steffen. N., Becker P.B., Erhardt, S. The histone-fold protein CHRAC14 influences chromatin composition in response to DNA damage. Cell Reports 7, 321-330, doi:10.1016/j.celrep.2014.03.008 (2014).
Bade, D., Pauleau, A. L., Wendler, A. & Erhardt, S. The E3 ligase CUL3/RDX controls centromere maintenance by ubiquitylating and stabilizing CENP-A in a CAL1-dependent manner. Dev Cell 28, 508-519, doi:10.1016/j.devcel.2014.01.031 (2014).
The ideal candidate for this PhD position is a highly motivated and interactive person with a strong background in cell biology and molecular biology, a strong interest in chromatin biology and epigenetic processes and enjoys being part of an international and collaborative team
While applying for the job please refer to jobvector and use the following reference number: Erhardt0216
A pre-check of materials or eligibilty is not possible.
The Hartmut Hoffmann-Berling International Graduate School of Molecular and Cellular Biology (HBIGS)
Im Neuenheimer Feld 501 (HBIGS Center), 1st floor
T: +49 6221-546720
F: +49 6221-546718
About Universität Heidelberg - ZMBH
The primary goal of the research in my group is to elucidate how epigenetic mechanisms are linked to centromere identity, chromosome segregation, and cell cycle progression. We use diverse cell biological, biochemical, molecular and genetic tools in the fruit fly Drosophila melanogaster and human cell culture for our studies. We have identified regulators that functionally or physically...More about Universität Heidelberg - ZMBH