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Role of lipid mediators in immunometabolic disorders OR Structure-function studies of enzymes in the arachidonic acid cascade

Else Kröner-Fresenius PhD studentship
in Stockholm in the laboratory of Prof. Dr. Jesper Haeggström, Karolinska Institute
  • Studies of the role of lipid mediators in immunometabolic disorders such as diabetes and cardiovascular diseases. This project will involve pharmacological studies of metabolic receptors in various immune cells and their link to lipid mediator signaling.
  • OR
    Structure-function studies of enzymes in the arachidonic acid cascade and related drug development efforts. The focus will be on biochemical and biophysical studies of recombinant enzymes and development of enzyme inhibitors.
The Else Kröner-Fresenius Research Training Group “Eicosanoid and sphingolipid pathways in inflammation, cancer and vascular diseases” is an international research training group at the Goethe University Frankfurt and the Karolinska Institute in Stockholm and is funded by the Else Kröner-Fresenius-Stiftung.  The focus of this research training group is on intensifying the understanding of the physiological and pathophysiological roles of eicosanoids and sphingolipids in inflammatory processes, cancer and vascular diseases. The molecular mechanisms of actions will be investigated using complementary approaches (chemical, biochemical, molecular, pharmacological, physiological and preclinical).  The academic goal is to train excellent graduate students for careers in molecular medicine, pharmacy and biology both in academia and industry. 
Candidates should already possess a first class MSc (biology, pharmacy or related discipline) or an MD degree.  Applications consisting of a cover letter indicating motivation and project references as well as a full curriculum vitae containing a brief summary of previous research projects, together with copies of all relevant university certificates should be sent by email to Dr. Brigitte Held (  Hard copy version can be to the postal address:  Dr. Brigitte Held, Institut für Pharmazeutische Chemie, Goethe Universität Frankfurt, Max-von-Laue-Str. 9, D - 60438 Frankfurt.  Incomplete applications will not be considered.
The application deadline is July 22nd, 2016.  Short listed applications will be required to attend a selection workshop in Frankfurt.
Stipends will be paid according to the rules of the Deutsche Forschungsgemeinschaft (DFG).
For further information on the projects as well as FIRST, please visit:
How to apply:
Applications by email preferred.
Send application to
Dr. Brigitte Held
Institut für Pharmazeutische Chemie
Goethe Universität Frankfurt
Max-von-Laue-Str. 9
D - 60438 Frankfurt. 
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About Johann Wolfgang Goethe Universität Frankfurt am Main

The graduate centre FIRST is a unique organization of the Johann Wolfgang Goethe University of Frankfurt, the Georg Speyer Haus (GSH) and the Paul Ehrlich Institute (PEI) in Langen. At Frankfurt University, groups within the faculties Medicine (FB16) and Biochemistry, Chemistry and Pharmaceutical Sciences (FB14) that address different aspects of drug research from basics up to clinical...

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