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Two MSc. Theses subjects available on RNAi in plant-microbe interaction

Two MSc thesis positions are currently available in the Weiberg Group (LMU, Department for Genetics, Faculty of Biology).
In the first MSc project, the interaction between Arabidopsis thaliana and its highly adapted pathogen Hyaloperonospora arabidopsidis will be studied. Preliminary data including next-generation sequencing data indicate a role of non-coding small RNAs during the infection process. To validate the role of small RNAs, the aim of this project is to establish a novel RNAi fungicide approach by direct application of RNAs onto the plant surface. This method can be a starting point into GMO-free and highly specific RNAi plant protection strategy. The MSc candidate will work in a team with a PhD student and will learn and apply state-of-the-art molecular tools currently used in RNAi research.
The second MSc project focuses on the role of small RNA biogenesis in the plant pathogenic fungus Botrytis cinerea . The MSc candidate will work on establishing the revolutionary genome editing technique CRISPR-Cas9 in B. cinerea , to generate knockout mutants of small RNA pathway genes. Generated mutant strains will be directly tested for altered virulence in a tomato infection assay. Exploring the role of small RNA pathways in microbial pathogens bares great potential to discover novel targets for plant protection strategies.
Highly motivated and talented Master students with great interest in plant and microbial molecular research are invited to contact Dr. Arne Weiberg ( for an interview appointment or gain further information about project details.

How to apply:
Send application to
Dr. Arne Weiberg
Ludwig-Maximilians University (LMU)
Biocenter, Department for Genetics
Großhadener Strasse 2-4
82152 Martinsried
phone: +49-89-218074731
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