Groupleader Upstream Process Development (Biotechnology, Bioengineering)

CEVEC Pharmaceuticals is a center of expertise for the production of biopharmaceuticals using a unique human cell expression system.
The CAP®GT cell platform, as one of our core technologies, provides a unique system for the industrial production of viral vectors. Our second core technology, the CAP®Go expression platform, comprises a portfolio of glyco-optimized human suspension cell lines for tailor-made glycosylation of recombinant proteins.

Cevec Pharmaceuticals is offering a position for a
Groupleader Upstream Process Development

Activities and responsibilities

  • Development of upstream processes from benchtop to pilot scale in close interaction with internal and external customers.
  • Characterization and optimization of processes in scale down models (ambr15).
  • Transfer of optimized processes to the GMP manufacturing facility, including consulting and guiding.
  • Document and maintain corresponding SOPs and batch-specifications. Write project plans and scientific reports.
  • Supervise and train technical assistants.
  • Work in close collaboration with our external partners.

Qualification profile

  • You hold a Ph.D. in Biotechnology, Bioengineering, or equivalent and you have at least 3 years work experience in commercial biopharmaceutical protein or viral vector manufacturing.
  • Extensive mammalian cell culture technology experience
  • You have extensive knowledge of scale-up of mammalian cell culture manufacturing processes into commercial scale.
  • Experience with high throughput scale-down micro-bioreactors, benchtop, and single-use bioreactors is highly desirable. Experience in operating perfusion bioreactor culture systems is a strong plus.
  • You possess knowledge in using design-of-experiment (DoE) and other experimental methodologies to support process improvements.
  • You have experience in leading a team, furthermore you are a strong team player with excellent English communication skills, both oral and written.

Benefits

We offer outstanding development opportunities in the young team of a fast-growing technology company with a strong proprietary intellectual property portfolio, friendly working environment, modern laboratory equipment and attractive remuneration.

Send application to

Anja Pawelzick
career@cevec.com
CEVEC Pharmaceuticals GmbH
Gottfried-Hagen-Str. 60-62, 51105 Köln

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About CEVEC Pharmaceuticals GmbH

CEVECs Geschäftsfelder sind die Entwicklung einer neuen Plattform-Technologie für die Produktion von Biopharmazeutika auf der Grundlage proprietärer humaner Zelllinien (CAP-Zellen), und die Entwicklung ausgewählter biopharmazeutischer Produkte.   

More about CEVEC Pharmaceuticals GmbH