Biotechnlogist - Transposon-based Genome Engineering, Primary Cell & Cell Line Culture / Transfection, Flow Citometry (m/w/d)

Everyone can achieve great things at BioNTech! We develop revolutionary approaches in the fight against cancer and other diseases. BioNTech wants to become the world’s leading biotechnology company for individualized cancer medicine. Over 1000 dedicated, passionate pioneers achieve sensational success and promising breakthroughs time and again by forging new paths – and ensure people all around the world have hope for the future. You too can become a pioneer!


Transposon-based Genome Engineering

Here, you’ll achieve greatness.

At BioNTech, you will play a major role in one of our collaboration projects because you will be responsible for the validation of therapeutic genome engineering of B cells with transposon and CRISPR/Cas genomic tools. Your duties in detail:
  • Establishing and optimizing in-vivo and ex-vivo transposon-based gene delivery procedures for gene therapy in B cells
  • Independent conducting of cell culture and molecular-biology based studies, experiments and documentation
  • Vector design, cloning and implementation of molecular biology-based assays for transposon insertion site profiling in B cells
  • Generation of SOPs for established methods
  • Independent design of experimental procedures and assays

What you have to offer.

  • Completed PhD studies in the field of genome engineering or similar as well as several years of professional experience. Ideally, experience in using transposon-based gene delivery methods
  • Experience in culture and transfection of primary cells and cell lines, flow citometry and cell line generation. Practical experience in culture and analysis of immune cells (T and B cells) is an advantage
  • Experience in basic and advanced molecular biology techniques such as various cloning techniques (cut-and-paste, Gibson assembly, Cold Fusion etc.), PCR based assays (practical knowledge of ddPCR and Q-PCR are a plus), genomic DNA isolation and analysis
  • Deeper understanding of established cell and molecular biology assays and processes
  • Experience in analysis, interpretation and presentation of experimental data

Benefits for you.

  • Jobticket
  • Child Care
  • Company Bike
  • Fitness
  • Pension
  • Relocation
...and much more.

Have we kindled your pioneering spirit?

Then apply now for our location Mainz and simply send us your application documents using our online form.

If you have any further questions, Friederike Mangelsen will be happy to answer them on + 49 (0) 6131-9084-1291 (monday-friday, from 12 noon).

*BioNTech does not differentiate on the basis of gender, race, religion, color, origin, sexual orientation, disability, age and other protected status as required by applicable law. We are committed to creating a diverse environment and are proud to be an equal opportunity employer.
BioNTech - As unique as you

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About BioNTech SE

Bei BioNTech leistet jeder Großes! Denn als eines der am schnellsten wachsenden Biotechnologie-Unternehmen Europas arbeiten wir an revolutionären Ansätzen im Kampf gegen Krebs und andere Krankheiten. Über 1000 Pioniere, die mit viel Herzblut neue Wege beschreiten, schaffen immer wieder aufsehenerregende Erfolge und vielversprechende Durchbrüche – und sorgen dafür, dass Menschen rund um die Welt...
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