Master thesis “Method development for the characterization of glycosyltransferases and in-vitro enzyme cascade”

The Max Planck Institute for Dynamics of Complex Technical Systems in Magdeburg, Bioprocess Engineering (Prof. Dr.-Ing. Udo Reichl), has an opening for a
 
Master Thesis / Internship in Biotechnology / Process Engineering / Analytical Chemistry
 
“Method development for the characterization of glycosyltransferases and
in-vitro enzyme cascade”
 
 
Background
Glycosylation is an important modification of proteins, and is involved in the regulation of biological activity and stability of many proteins. Notably, the glycosylation of many eukaryotic proteins appears to be highly-regulated and minor structural changes of glycan portions may lead to enzyme dysfunction. Research into glycosylation has, thus, profoundly increased over the last years and controlling protein glycosylation is seen as a key for the cost-effective manufacturing of biotechnological products.  In a joint project, an in-vitro enzyme cascade is build up to produce glycans enzymatically. Detection and quantification of glycans and sugar nucleotides by high performance anion exchange chromatography (HPAEC) and high performance multiplexed capillary gel electrophoresis with laser-induced fluorescence detection (xCGE-LIF) requires highly efficient and novel methods. We offer an exciting project in the cross section of bioengineering and bioanalytics with the opportunity to work with state-of-the-art equipment and first-class training and supervision.  
 
Requirements
  • Background in biotechnology, chemical engineering or analytical chemistry
  • Ideally, experience with bioanalytical methods
  • Motivation, curiosity and ability to work in a team
 
We offer
  • Exciting research projects and the opportunity to develop key technologies
  • First-class supervision and thorough training by our staff
  • Training on state-of-the-art equipment for biotechnological research and development
  • Acquisition of expertise in a key technology of the future

Start: March 2017

Application
Applications in German or English are welcome. Please include your CV and transcript of records. Please submit your application until February 28th, 2017

Note that applications from women are especially welcome and that the Max Planck Society is committed to employing disabled individuals and encourages them to apply.

Contact detail


How to apply:
Only by email as 1 pdf document!
Send application to
Contact
Dr. Thomas Rexer
E-Mail: rexer@mpi-magdeburg.mpg.de
Phone: +49 (0) 391 6110 375

 

Job profile


Working hours
Full-Time
Contract duration
Permanent
Type of job
Diploma Thesis/Master's Thesis
Work experience
job experience is not required
Region
Germany (Sachsen-Anhalt)
Working place
39106 Magdeburg
Area of expertise
Biotechnology, Biology & Life Sciences, Chemistry, Chemical & Process Engineering
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About Max Planck Institute for Dynamics of Complex Technical Systems

In 1996 the Max Planck Institute for Dynamics of Complex Technical Systems was established. The foundation director is Prof. em. Dr.-Ing. Ernst Dieter Gilles. The institute in Magdeburg is the first institute of the Max Planck Society dedicated to the engineering sciences and is supposed to bridge the gap between basic research and industrial applications. The neighbourhood to the Otto...

More about Max Planck Institute for Dynamics of Complex Technical Systems

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