Scientist (Bio-)Chemistry, Biotechnology, Biochemical Engineer as Biologics Downstream Process Specialist (m/f/d)

 PIERIS Pharmaceuticals GmbH  Freising bei München
Pieris Pharmaceuticals is a publicly traded biotechnology company (Nasdaq: PIRS) with operations in Germany and the United States, specializing in the discovery and development of anticalin-based drugs to address validated disease pathways individually and transformatively. Together with our partners, we carry out innovative research in the fields of immuno-oncology, respiratory diseases and ophthalmology. Pieris' proprietary Anticalin proteins are a novel class of drugs validated by clinical trials and partnerships with leading pharmaceutical companies.

To strengthen our team, we are looking for an experienced:

Biologics Downstream Process Specialist (m/f/d), CM

Your Tasks:

  • Support process development, process fit analysis, technical transfer, scale-up and cGMP manufacturing at our CDMO sites.
  • Maintain a strong working relationship with internal and external partners in the areas of trouble-shooting, technology review and new product manufacturing implementation. 
  • Prepare management decisions and communicate project updates to the relevant project governance meetings and steering committee. 
  • Lead investigation into any purification related deviations. 
  • Identify, mitigate and escalate project risks in downstream process development and manufacturing.
  • Author and review reports and technical documents supporting regulatory filing.

Our Requirements:

  • Ph.D. or M.Sc. in biochemistry, chemistry, biotechnology, biochemical engineering or a related discipline in life-science.
  • 4+ years of experience in downstream processing within the biopharmaceutical industry.
  • Comprehensive understanding and experience with Good Manufacturing Practices (cGMP) 
  • Experience in purification process development, process transfers, in support of cGMP manufacturing and technical trouble shooting. 
  • Proficient with downstream operations such as centrifugation, filtration, chromatography, buffer preparation, cleaning and sanitization and any in-process analysis needed to evaluate purification performance. 
  • Experience in interfacing with health authorities on regulatory CMC filings and audits. 
  • Additional experience with USP is an advantage. 
  • Team player with highly structured approach and well-developed communication skills 
  • Ability to travel is required. 


We are a fast-growing biotechnology company with approximately 120 employees at our sites in Freising (Greater Munich Area) and Boston (USA). We work in flat hierarchies with short decision-making paths and offer a working environment characterized by cooperation and innovation.

Each of our employees participates directly in the success of the company through a stock option program and a stock savings plan. In addition, each employee participates in a bonus program based on the achievement of individual and company-wide goals. Creative employee events take place several times a year, as team spirit is essential for us. The joint creation of an innovative and participative corporate culture is an important concern for us.

While applying for the job please refer to jobvector

About PIERIS Pharmaceuticals GmbH

Pieris Pharmaceuticals GmbH is a subsidiary of Pieris Pharmaceutical Inc., a public US company. Pieris Pharmaceuticals GmbHis a clinical-stage biotechnology company advancing its proprietary Anticalin® technology to create differentiated drugs that are safer and more effective than conventional approaches. Exclusive to Pieris, Anticalin proteins promise to address high-unmet medical needs and...

More about PIERIS Pharmaceuticals GmbH