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PhD Position

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One PhD position is now available at the Clemens-Schöpf-Institute for Organic and Biochemistry (Darmstadt, Germany) for an enthusiastic, highly-motivated, hardworking individual to work on the research in our laboratory within the State of Hessen's LOEWE Program for Scientific and Economic Excellence “iNAPO” (Ion-conducting Nanopores) project on the topic entitled “Chemical Synthesis of Protein Nanopores on the Basis of Ion Channels and Pore-forming Peptides”.
 
Requirements
Applicants should have a Diploma or Master degree in Chemistry, Biomolecular engineering, Biochemistry, Biotechnology or Pharmacy. We are seeking for highly motivated people wishing to pursue their career in science with a competitive CV (Master-Thesis score: “sehr gut” in the German score system), regular period of study, capacity for team working and ability to perform independent work. Applicant should have an integrative and cooperative personality with enthusiasm for actively participating in “iNAPO” network with very good communication and writing skills (English).
 
Project field
In living organisms the transport of ions is performed by ion channels and transporters. Basic principles of the working mechanism and the reason for their efficiency/high selectivity are good understood to date. This information will help us to develop ion-selective pores for various technical applications in biophysical, biochemical and medical fields. Within the project we will construct in analogy to biological systems the membrane protein channels. In combination with the polymeric support/lipids we will use the advantageous functions of membrane proteins to develop robust ion-conducting pores. The selected candidate will chemically synthesize and modify membrane proteins to achieve the project goal. The project is integrated into the highly collaborative research environment at the TU Darmstadt comprising experts from biology, chemistry, physics, material science and electrical engineering
 
Methods
  • Solid phase peptide synthesis
  • Liquid-phase synthesis (Organic chemistry)
  • Analytical and preparative HPLC, Mass spectrometry (ESI-MS and MALDI-TOF MS)
  • NMR and CD spectroscopy
  • Computational structural biology

Contact detail


How to apply:
written form
Send application to
Please address enquiries until February 29th, 2016, including CV with academic transcript plus grades and reference letter to: 
Junior Research Group Leader, Dr. Alesia Tietze, a.tietze@biochemie-TUD.de 

Job profile


Working hours
Full-Time
Contract duration
Temporary
Type of job
PhD Project
Work experience
job experience is not required
Region
Germany (Hessen)
Working place
64287 Darmstadt
Area of expertise
Chemistry, Biology & Life Sciences
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