PhD (m/w/d), Biology, Biophysic related field

In vitro models of the human endometrium for cell biological and clinical implantation studies 
30% of all pregnancies are lost during the early implantation phase. To increase the success rates of assisted reproductive technologies, a better understanding of the cellular mechanisms of this initial pregnancy phase is required. The project will focus on mechanical aspects of embryo implantation and the interaction between maternal and embryonic epithelia - i.e. the invading trophoblast and the barrier-forming uterine epithelium - via cell-cell contacts and their hormonal regulation.

Activities and responsibilities

  • perform co-culture experiments with endometrial and trophoblast cell lines as well as with primary cells in an in vitro system for the investigation of endometrial receptivity
  • assess co-cultures by means of confocal and traction force microscopy
  • analyze mechanical cues of trophoblast-endometrial interaction

Qualification profile

  • master degree in biology, biophysics or related field
  • expertise in histology, microscopical techniques, image analysis, cell culture methods
  • with a background in cell biology and / or biophysics.

Benefits

The position is offered as an partime position (25,03 h/w) and project related for three years. There will be the option to extent the contract. The salary corresponds to level 13 TV-L.

Send application to

to: H. Dr. Volker Buck, Institute of Molecular and Cellular Anatomy, Wendlingweg 2, RWTH Aachen University, D-52057 Aachen.E-Mail: vbuck@ukaachen.de

While applying for the job please refer to jobvector and use the following reference number: GB-P 15836

About Universitätsklinikum Aachen

Die Zukunftschancen des Universitätsklinikums Aachen und der Medizinischen Fakultät der RWTH Aachen beruhen auf der Verbindung von konsequenter Patientenorientierung, effizienter Lehre und innovativer Forschung. Diese geschieht in enger Kooperation mit den ingenieur- und naturwissenschaftlichen Disziplinen der Hochschule. Für die Erfüllung aller Ziele ist wirtschaftliches...

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